5-tert-butyl 2-ethyl 6,7-dihydrothiazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate(CAS#1053656-51-1)
Introduction
5-tert-butyl 2-ethyl 6,7-dihydrothiazol[5,4-C]pyridine-2,5(4H)-dimethyl ester is an organic compound with a chemical structure of C19H26N2O4S.Quality:The compound is a white solid with special chemical properties and structure, and is soluble in organic solvents such as ether, acetone, and chloroform. It is sensitive to light and should be stored in a dark, dry place.Use:This compound has some useful applications. It can also be used as a synthetic intermediate for dyes and pigments.Method:This compound is usually prepared using organic synthetic chemistry. Specifically, 2-ethylpyridine is often used as the starting material, and the target compound is finally obtained after a series of chemical reaction steps, such as alkylation, carbonylation, condensation, etc.Safety Information:Although there is no clear safety data, appropriate safety measures should be taken when handling this compound. Direct contact with the skin, inhalation, or accidental ingestion should be avoided. During the operation, appropriate protective gloves, masks, and goggles should be worn. Avoid operating in unventilated places, and keep away from fire sources and high-temperature places. If accidentally touched, inhaled or ingested, it should be washed or treated with medical attention in time.
Application
5-tert-Butyl 2-ethyl 6,7-dihydrothiazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate (CAS 1053656-51-1) is a specialized bicyclic heterocycle featuring orthogonal ester protecting groups. This building block is widely used in medicinal chemistry for the synthesis of selective kinase inhibitors, particularly targeting PI3K, CDK, and BTK families for cancer and autoimmune disease therapies. The tert-butyl and ethyl esters enable stepwise deprotection and orthogonal functionalization, allowing rapid construction of diverse drug-like libraries. Its rigid thiazolo-pyridine core enhances metabolic stability and target binding affinity. This intermediate is also utilized in the development of antiviral, antibacterial, and anti-inflammatory agents. High purity ensures reproducible results in SAR studies and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this essential scaffold with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.

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