5,6-DiaMino-3-Methyl-1H-pyriMidin-2,4-dion(CAS#40959-24-8)
5,6-DiaMino-3-Methyl-1H-pyriMidin-2,4-dion(CAS#40959-24-8)
Physicochemical properties
Properties: Usually white or off-white crystalline powder.
Melting Point: It has been reported in the literature to have a melting point of around 290 - 295°C, and decomposition occurs at high temperatures.
Solubility: slightly soluble in water, solubility in organic solvents such as ethanol, methanol, dichloromethane, etc. is relatively poor, but soluble in some highly polar solvents such as dimethyl sulfoxide (DMSO), N, N-DIMETHYLFORMAMIDE (DMF), etc.
Structural features
The molecule contains a pyrimidine ring structure, which is an important nitrogen-containing heterocyclic with certain aromaticity and stability.
Positions 2 and 4 on the ring are two carbonyl groups (C=O), positions 5 and 6 are two amino groups (-NH₂), and position 3 is a methyl group (-CH₃). Carbonyl and amino groups can form a variety of hydrogen bonds and conjugated systems, which have an important impact on the physicochemical properties and biological activity of compounds.
Fields of application
In the field of medicine, this compound can be used as an important pharmaceutical intermediate for the synthesis of some biologically active pyrimidine drugs. In the field of agriculture, it may be used to synthesize new pesticides, plant growth regulators, etc., to provide guarantee for agricultural production.
Application
5,6-Diamino-3-methyluracil (5,6-Diamino-3-methyl-1H-pyrimidine-2,4-dione, CAS 40959-24-8) is a versatile heterocyclic building block with a pyrimidinedione core containing two amino groups and a methyl substitution. In pharmaceutical R&D, this compound serves as a key pharmaceutical intermediate for constructing biologically active pyrimidine-based drugs. Research indicates its derivatives exhibit antiviral activity (e.g., against influenza virus) and anticancer properties via cytotoxic effects on cancer cell lines. The compound also functions as an enzyme inhibitor, interfering with nucleotide metabolism enzymes such as dihydropteroate synthase and thymidylate synthase. In agrochemical research, 5,6-diamino-3-methyluracil is utilized as a versatile building block for synthesizing new pesticides, fungicides, and plant growth regulators, providing effective crop protection solutions. Its reactivity and hydrogen-bonding capacity make it a valuable scaffold for library construction in drug discovery. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 5,6-diamino-3-methyluracil with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.


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