betulinic acid(CAS#472-15-1)
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29181985 |
Introduction
Betulinic acid, also known as birch rosin, is a rosin-like compound composed of fatty acids and camphoric acid found in the birch tree. The following is an introduction to the properties, uses, preparation methods and safety information of betulinic acid:Quality:Appearance: Betulinic acid is a white color or a crystalline solid similar to camphor.Solubility: Betulinic acid is soluble in alcohols, ethers, and organic solvents, but insoluble in water.Use:Method:The preparation method of betulinic acid is generally obtained by distilling and extracting a mixture of fatty acids and camphoric acid from birch bark. The birch bark is first crushed and pulverized, then the mixture is extracted with an appropriate organic solvent, and then crystallized by distillation and cooling to obtain betulinic acid.Safety Information:The use of betulinic acid is generally safe, but proper handling and use methods should still be followed.Exposure to betulinic acid may cause skin irritation, and prolonged or heavy exposure should be avoided when using the product.If accidental exposure to betulinic acid causes discomfort, rinse immediately with plenty of water and consult a doctor.Caution should still be exercised during use and appropriate safety measures should be followed.
Application
Betulinic acid is a naturally occurring pentacyclic triterpenoid widely used as a pharmaceutical research standard and bioactive cosmetic ingredient. It exhibits potent anticancer properties by inducing apoptosis in various cancer cell lines, including melanoma and glioblastoma, and demonstrates anti-HIV activity as a maturation inhibitor. Its derivatives have advanced to clinical trials for AIDS and cancer treatment. In dermatology, betulinic acid is formulated into topical oleogels and nanostructured lipid carriers for enhanced skin penetration, offering anti-inflammatory, antimicrobial, and wound-healing benefits. The compound also shows antidiabetic, antimalarial, and antioxidant activities. As a natural, clean-label ingredient, betulinic acid is increasingly incorporated into nutraceutical supplements for immune support. Xinchem provides reliable custom chemical synthesis and contract manufacturing of high-purity betulinic acid with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and global supply.
