2-Amino-5-methylbenzoic acid(CAS#2941-78-8)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29224999 |
| Hazard Class | IRRITANT |
Introduction
2-Amino-5-methylbenzoic acid is an organic compound, often abbreviated as AMPA. The following is an introduction to its nature, use, preparation method and safety information:Quality:- Appearance: White crystalline powder- Solubility: Slightly soluble in water and easily soluble in organic solvents such as ethanol and ether- Chemical reactions: Its amino and carboxyl groups can undergo covalent bonds to form various compoundsUse:- Research Use: Commonly used as an agonist to study neurotransmitter glutamate-related signaling pathwaysMethod:- The common preparation method is obtained by amination of 2-methylbenzoic acid. Specifically, the reaction of 2-methylbenzoic acid with an amination reagent, such as ammonia or ammonia solution, is usually carried out in a reaction solvent, such as ethanol. After the reaction, the target product can be purified by crystallization.Safety Information:- 2-Amino-5-methylbenzoic acid is a general chemical with certain hazards, and the following safety measures should be paid attention to when operating:- Avoid inhaling its dust or gases and avoid contact with skin and eyes- Wear protective gloves, goggles, and masks when operating- Keep the operating area well ventilated- Follow relevant safety operating procedures for proper storage and disposal of the compound.
Application
2-Amino-5-methylbenzoic acid is a functionalized aromatic compound used as a key pharmaceutical building block. It is a critical precursor in the synthesis of various drug molecules, notably as the starting material for the anti-cancer drug Raltitrexed. This versatile intermediate is also employed to synthesize quinazolinedione and in solution-phase peptide synthesis. Its pharmaceutical applications extend to the preparation of anti-inflammatory and analgesic drugs. Additionally, it serves as Cetilistat Impurity 5, making it an essential reference standard for analytical method development and quality control. In biochemical research, it is used in studies of amino acid metabolism. Xinchem offers high-purity 2-Amino-5-methylbenzoic acid with reliable global supply. Contact us for a competitive quote.
