page_banner

product

Cloprostenol sodium(CAS#55028-72-3)

Chemical Property:

Molecular Formula C22H28ClO6.Na
Molar Mass 446.9
Melting Point 68-70°C
Boling Point 628°C at 760 mmHg
Flash Point 333.6°C
Solubility H2O: >10mg/mL
Vapor Presure 1.23E-16mmHg at 25°C
Appearance solid
Color light brown
Storage Condition Inert atmosphere,Store in freezer, under -20°C
In vitro study Cloprostenol is a PGF2α receptor agonist. Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days.
In vivo study Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats.

Product Detail

Product Tags

Cloprostenol sodium(CAS#55028-72-3)

properties
Appearance: White to almost white hygroscopic powder.
Melting Point: 68 - 70 ºC.
Boiling Point: 628°C (at 760mmHg)
Flash Point: 333.6ºC.
Solubility: Soluble in water, solubility in water greater than 10mg/mL.
LogP:1.86030, reflecting the relative degree of lipophilicity and hydrophilicity.
PSA: 110.05000, that is, the polar surface area, which has an effect on the water solubility, biological activity, etc. of the compound.
Fields of application
Cloprostenol sodium is a potent FP receptor agonist with luteal solubility and is an agonist of the PGF2α receptor. It has an important application in the field of animal husbandry, mainly used to control the estrous cycle of female animals, promote the estrus of female animals at the same time, and improve reproductive efficiency. It can also be used to induce abortion in female animals, treat reproductive disorders such as persistent corpus luteum and pyometra, help maintain good reproductive health status of female animals, and improve the production efficiency of animal husbandry.

Application
Cloprostenol sodium is a potent synthetic analog of prostaglandin F2α (PGF2α), primarily used as a veterinary API for luteolysis, estrus synchronization, and the treatment of reproductive disorders in cattle, swine, and horses. It is the active ingredient in commercial products such as Estrumate® and SYNCHSURE®. Cloprostenol sodium works by inducing functional and morphological regression of the corpus luteum, which rapidly lowers progesterone levels and allows for the precise control of the estrous cycle. This action is key for timed artificial insemination (TAI) protocols, the termination of pregnancy due to mismating, and the management of conditions like pyometra and chronic endometritis. Xinchem offers high-purity Cloprostenol sodium with flexible custom synthesis, custom chemical synthesis, and reliable contract manufacturing, scaled from R&D to commercial GMP tons. Contact us today for a competitive quote and global veterinary supply.


  • Previous:
  • Next:

  • Write your message here and send it to us