cyclohexylacetone(CAS#103-78-6)
Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R36 - Irritating to the eyes R52 - Harmful to aquatic organisms |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| TSCA | Yes |
cyclohexylacetone(CAS#103-78-6) introduction
Cyclohexylacetone is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of cyclohexylacetone:
1. Nature:
- Appearance: Cyclohexylacetone is a colorless to pale yellow liquid.
- Odor: A pungent aromatic odor.
- Solubility: Cyclohexylacetone is soluble in a variety of organic solvents, such as ethanol, ether and acetic acid.
2. Usage:
- Cyclohexylacetone is used as an important solvent in industry and is widely used in coatings, inks and adhesives.
- It can also be used as an intermediate in the synthesis of organic compounds and participates in the reaction of ketones and alcohols.
3. Method:
Cyclohexylacetone is formed by the reaction of acetylacetone (or acetone and acetone) with ferrous chloride.
4. Safety Information:
- Cyclohexylacetone is an organic compound and is potentially hazardous and should be handled safely.
- Avoid contact with skin, eyes, and respiratory tract. In case of accidental contact or inhalation, wash the skin and rinse the eyes with water.
- During storage and use, it should be kept away from fire sources and high temperatures to prevent fire or explosion.
- Ensure that you operate in a well-ventilated area and use appropriate protective equipment such as gloves, goggles, and protective clothing.
Application
Cyclohexylacetone (1-Cyclohexylpropan-2-one, CAS 103-78-6) is a versatile cyclic ketone used as a key intermediate in pharmaceutical, agrochemical, and fragrance synthesis. In drug discovery, it serves as a building block for the preparation of antispasmodic agents, bronchodilators, and analgesics. Its reactive methylene group enables aldol condensations and Michael additions, facilitating the construction of complex heterocyclic scaffolds. As a fragrance raw material, cyclohexylacetone imparts a warm, floral, and slightly fruity note to perfumes, soaps, and detergents. It is also employed as a solvent for cellulose esters and resins in coatings and inks. In organic synthesis, this ketone undergoes Baeyer-Villiger oxidation, Grignard additions, and reductive aminations. Its high purity ensures reproducible results in custom chemical synthesis and scale-up. Xinchem offers custom synthesis and contract manufacturing of high-purity cyclohexylacetone with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.



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