Ethyl 6,8-dichlorooctanoate(CAS#1070-64-0)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
Ethyl 6,8-dichlorooctanoate(CAS#1070-64-0)
quality
Ethyl 6,8-dichlorooctanoic acid is an organic compound. It is a colorless to pale yellow liquid with a spicy flavor. Ethyl 6,8-dichlorooctanoic acid is insoluble in water at room temperature, but can be soluble in organic solvents such as ethanol and ether.
This compound has good solubility and can be used as a solvent or reaction feedstock. It is often used as a solvent for coatings, paints and resins, and can also be used for esterification reactions in organic synthesis and the preparation of ethers.
The main harm of ethyl 6,8-dichlorooctanoic acid is its irritation and damage to the human body. Exposure to or inhalation of the substance may cause irritating symptoms such as irritation of the eyes and respiratory tract, dry and itchy skin. Long-term or heavy exposure can cause damage to the central nervous system and liver.
When using or handling ethyl 6,8-dichloroocanoate, appropriate safety measures should be taken, including wearing protective gloves, goggles, and respiratory protective equipment, and ensuring that it is operated in well-ventilated conditions.
Application
Ethyl 6,8-dichlorooctanoate (CAS 1070-64-0) is a key pharmaceutical intermediate and organic building block for the multi-step synthesis of α-lipoic acid (thioctic acid), a potent naturally occurring antioxidant with therapeutic applications in diabetic neuropathy, cardiovascular diseases, Alzheimer's disease, and as a dietary supplement for cellular energy metabolism. As a high-purity dichlorinated fatty acid ester, it enables the preparation of α-lipoic acid derivatives, including 6-selenolipoic acid, 6,8-dibenzylmercaptooctanoic acid, and ethyl 5,7-dichloroheptanoate, which are valuable in drug discovery and oncology research for their potent anticancer activity. It is also used as an essential raw material for the manufacture of lipoamide and vitamin-like drugs. Beyond pharmaceutical synthesis, this compound serves as an analytical reference standard for method development (AMD), method validation (AMV), quality control (QC) in ANDA filings, and commercial production of thioctic acid, ensuring traceability to USP or EP pharmacopeial standards. With flexible custom synthesis and contract manufacturing capabilities, Xinchem provides high-purity Ethyl 6,8-dichlorooctanoate scaled reliably from R&D to commercial tons. Contact us for a competitive quote and global supply.
