Magnesium 3-Hydroxybutyrate BHB Magnesium(CAS#586976-57-0)

1. Properties:

• Appearance and Physical Form: Magnesium 3-hydroxybutyrate is a white to off-white crystalline powder. It is highly soluble in water, making it easy to incorporate into a wide range of nutritional formulations.
• Solubility: The compound is easily soluble in water, a key characteristic for its use in drink mixes and other liquid supplement formats.
• Chemical Properties: Magnesium 3-hydroxybutyrate (C₈H₁₄MgO₆) is the magnesium salt of 3-hydroxybutyric acid, a natural "ketone body" produced during fat metabolism. Its structure comprises two 3-hydroxybutyrate anions coordinated to a single magnesium cation (2:1 salt).
  • Energy Metabolism: BHB is a primary circulating ketone body that serves as an alternative energy source for the brain, heart, and muscles, particularly during low carbohydrate intake or fasting. It delivers energy without requiring glucose metabolism.
  • Ketone Supplement: As an exogenous ketone salt, it raises blood ketone levels to help achieve and maintain ketosis, making it a key ingredient in ketogenic and sports nutrition products. The magnesium counter-ion provides essential mineral support.
  • GRAS Status: Magnesium 3-hydroxybutyrate is generally recognized as safe (GRAS) as a dietary supplement ingredient.

2. Applications:

Nutritional & Dietary Supplements (Primary Application):

• Ketogenic Supplements: Magnesium BHB is a popular ingredient in exogenous ketone supplements for supporting the state of ketosis.
• Sports Nutrition: It is used in pre-workout and recovery formulas to enhance athletic endurance, improve performance, and maintain energy levels.
• Mental Performance: BHB salts can serve as a fuel source for the brain, making them a component in "nootropic" or cognitive support supplements.

Research & Development:

• Metabolic Studies: Used as a research tool in studies related to energy metabolism, ketosis, and the effects of ketone bodies.
• Ingredient Innovation: Utilized in the development of new food and beverage products for the growing ketogenic and low-carb markets.

Other Applications:

• Cosmetics: Classified as a skin-conditioning agent and humectant in cosmetic formulations.
• Chemical Synthesis: Used as an intermediate in the production of other chemical compounds.

3. Preparation Method:

• Industrial Synthesis: Magnesium 3-hydroxybutyrate can be synthesized through the reaction of 3-hydroxybutyric acid with a magnesium base, such as magnesium hydroxide or magnesium oxide. In a typical process, 3-hydroxybutyric acid is neutralized with the magnesium compound in an aqueous solution. The product is then purified, crystallized, filtered, and dried to obtain the final white crystalline powder.

4. Safety Information:

• Hazard Classification: Magnesium 3-hydroxybutyrate is generally classified as a non-hazardous or low-hazard substance. It is considered a stable compound with no significant dangers under normal handling conditions. Not classified as a dangerous good for transport.
• Health Hazards:
  • Inhalation: May cause mild respiratory tract irritation if large amounts of dust are inhaled.
  • Skin Contact: May cause mild irritation upon prolonged contact.
  • Eye Contact: May cause mechanical irritation from dust particles.
  • Ingestion: Low acute toxicity. Intended for nutritional applications.
• First Aid Measures:
  • Eye Contact: Rinse cautiously with plenty of water for several minutes. Remove contact lenses if present and easy to do. If eye irritation persists, seek medical attention.
  • Skin Contact: Wash skin with plenty of soap and water.
  • Inhalation: Move person to fresh air. If symptoms persist, seek medical advice.
  • Ingestion: Rinse mouth. Do NOT induce vomiting. Seek medical attention if a large amount is ingested.
• Personal Protective Equipment (PPE):
  • Respiratory protection: Use a dust mask (N95 or P2 respirator) if airborne dust concentrations are present.
  • Eye protection: Safety goggles or dust-resistant safety glasses.
  • Skin protection: Chemical-resistant gloves (nitrile) and protective clothing.
  • General hygiene: Wash hands thoroughly after handling. Do not eat, drink, or smoke in work areas.
• Storage & Stability: Store in tightly closed, moisture-proof containers in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials. Protect from light. Under recommended storage conditions, magnesium 3-hydroxybutyrate has a shelf life of up to 48 months (4 years) from the date of manufacture in sealed original containers. It is non-hazardous and can be transported as general chemicals.
• Regulatory Compliance: Magnesium 3-hydroxybutyrate (CAS#586976-57-0) is listed on EINECS and TSCA. It is recognized as a safe dietary supplement ingredient (GRAS). This product is intended for research, development, and nutritional use and is not intended for medicinal, household, or other uses without proper authorization. Always consult the Safety Data Sheet (SDS) and local regulations for complete safety, environmental, and regulatory information specific to each product grade and application jurisdiction.