Methyl 3-Cyclohexenecarboxylate(CAS#6493-77-2)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 3272 |
| Hazard Class | 3 |
| Packing Group | III |
Introduction
Methyl 3-cyclohexene-1-carboxylic acid is an organic compound. It is a colorless liquid with a strong odor at room temperature. The following is an introduction to its properties, uses, manufacturing methods and safety information:Quality:Methyl 3-cyclohexen-1-carboxylic acid has good solubility and can be dissolved in many organic solvents, such as alcohols, ethers and aromatics.It is a stable compound that does not decompose or react easily.Use:Methyl 3-cyclohexen-1-carboxylic acid is an important intermediate in organic synthesis.It can also be used as a solvent and plasticizer in coatings, plastics and rubber industries, among others.Method:The preparation of methyl 3-cyclohexene-1-carboxylic acid is usually carried out by the following steps:Cyclohexene undergoes an oxidation reaction with air to form cyclohexenol.Then, cyclohexenol undergoes esterification reaction with formic acid to form methyl 3-cyclohexen-1-carboxylate.Safety Information:Methyl 3-cyclohexen-1-carboxylate is easily flammable at high temperatures, and contact with open flames and high-temperature surfaces should be prevented.Wear appropriate protective measures, such as safety glasses and gloves, during use to avoid direct contact with the skin and eyes.Avoid inhaling gases or vapours, and if inhaled, leave the contaminated area immediately and breathe into fresh air. If you feel unwell, seek medical attention promptly.
Application
Methyl 3-cyclohexenecarboxylate (CAS 6493-77-2) is a versatile cyclic ester used as a key pharmaceutical intermediate and specialty monomer. The compound undergoes enantioselective hydrolysis to produce (S)-3-cyclohexene-1-carboxylic acid, a critical chiral building block for the anticoagulant drug Edoxaban. It also serves as a precursor to methylcyclopentanone-3-carboxylate, which is used to synthesize the antitumor agent Sarkomycin. Beyond drug development, this cycloaliphatic ester finds applications in advanced polymer production, semiconductor manufacturing, and sensor technologies, where it contributes unique chemical properties to material formulations. Its unsaturated ring structure allows polymerization reactions for high-performance resins and coatings. As a versatile building block in organic synthesis, it supports the development of agrochemicals and fine chemicals. Xinchem offers custom synthesis and contract manufacturing of high-purity methyl 3-cyclohexenecarboxylate, providing flexible scaling from R&D to commercial tons with comprehensive analytical support. Contact us for a competitive quote.







