Product Name and CAS Number

p-Cresol 4 Methylphenol | CAS 106 44 5

One Line Sourcing Position

High purity p-Cresol for antioxidant synthesis, pharmaceutical intermediates, and specialty chemical applications.

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Specification

Purity by GC: 99.0 percent minimum, typical batch 99.2 to 99.6 percent
Appearance: Colorless to off white crystalline solid
Melting point: 34 to 36 deg C
Boiling point: 201 to 202 deg C
Water content Karl Fischer: 0.20 percent maximum
Solidification point: 33.5 deg C minimum
Residue on ignition: 0.05 percent maximum
Color APHA in methanol: 50 maximum
Heavy metals: Less than 10 ppm
Stock Status: In Stock in US warehouse and China hub

Available Quantity and Lead Time

Regular supply: 500 g to 20 metric tons per shipment
Lead time: 3 to 5 days for standard packaging; bulk orders require 7 to 10 days

Document Support

COA SDS HPLC chromatogram NMR spectrum Mass spectrum MS available upon request

Application

p-Cresol is a valuable intermediate in the production of antioxidants, particularly butylated hydroxytoluene (BHT) and other hindered phenol stabilizers used in plastics, rubber, and fuels. In pharmaceutical synthesis, it serves as a building block for the production of local anesthetics such as mepivacaine and ropivacaine, as well as for anti inflammatory and antiseptic agents. The agrochemical industry uses p-cresol to synthesize certain herbicides, fungicides, and insect repellents. In the flavor and fragrance sector, it contributes to smoky, phenolic notes in cheese, meat, and coffee flavors, and acts as a precursor for vanillin synthesis. p-Cresol is also employed in the manufacture of epoxy resin curing agents, phenolic resins, and as a raw material for photographic developers. In analytical chemistry, it is used as a reference standard for phenol derivative analysis by HPLC and GC MS. Additionally, it finds application in the production of specialty solvents, disinfectants, and as an intermediate for vitamin E synthesis.

Custom Synthesis Support

We offer custom synthesis for p-cresol derivatives including alkylated, halogenated, and nitrated products. Share your technical datasheet for feasibility review.

Packaging and Shipping

Available in 500 g, 1 kg, 25 kg fiber drums, or 200 kg net steel drums. Custom packaging such as HDPE containers with PTFE lined caps is supported. Fastest dispatch within 7 days after order confirmation. p-Cresol solidifies at room temperature; gentle warming to 40 deg C may be required for transfer. Class 6.1 toxic substance, UN 3455, PG II for international shipping.

Why XinChem

XinChem provides p-cresol with strict control of purity and impurity profile for US customers. Our ISO 9001 certified facility monitors every batch by GC and melting point analysis, ensuring consistent quality for antioxidant and pharmaceutical applications. We maintain a buffer stock of 5 metric tons in US warehouses for emergency deliveries within 48 hours. Each order includes a full documentation package: COA, SDS, GC chromatograms, and NMR spectra accessible through our online portal. Our technical support team assists with handling precautions, stability studies, and regulatory compliance including TSCA, EINECS, and REACH exemptions. For contract customers, we offer quarterly price locks and consignment inventory to reduce supply chain risk. Trusted by over 170 polymer additive and pharmaceutical companies in North America. We also provide free sample evaluation for qualified R&D projects and a price match guarantee against any valid competitor quote for equivalent quality. Safety data sheets and proper handling training are provided with each bulk shipment.

FAQ

Q1 How should p-cresol be stored safely?
A Store in a cool, dry, well ventilated area away from strong oxidizers and bases. Keep container tightly sealed. Shelf life is 24 months under recommended conditions.

Q2 What purity grades do you supply?
A Standard grade is 99.0 percent by GC. We also supply 99.5 percent and 99.8 percent grades for pharmaceutical and electronic applications.

Q3 Is p-cresol soluble in water?
A Slightly soluble in water (about 2.5 g per 100 mL at 20 deg C). Freely soluble in ethanol, diethyl ether, and acetone.

Q4 Do you provide sample quantities for formulation testing?
A Yes, free samples of 100 g are available for qualified US companies. Shipping fee applies for small quantities.

Q5 What safety measures are required when handling p-cresol?
A p-Cresol is toxic and corrosive. Use appropriate PPE including gloves, goggles, and lab coat. Work in a fume hood. For spills, use absorbent material and neutralization with sodium bicarbonate.

Q6 Can you supply p-cresol in molten liquid form for easier transfer?
A Yes, we can supply p-cresol as a molten liquid at 40 to 45 deg C in insulated tankers or heated totes. Please request for bulk orders.