Pyridazine, 3,6-dione, 4-bromo-1,2-dihydro(CAS#15456-86-7)
Introduction
4-Bromo-3,6-pyridazinedione, also known as bromopyridindione, is an organic compound. The following is an introduction to some of its properties, uses, manufacturing methods, and safety information:Quality:- Appearance: 4-bromo-3,6-pyridazinedione is a colorless crystal or light yellow solid.- Soluble: It is almost insoluble in water, but soluble in organic solvents such as ethanol, ethers, or ketones.Use:- As an insecticide, bromopyridine dione is used in agriculture for plant protection and can control some pests.Method:- The preparation method of 4-bromo-3,6-pyridazinedione is usually obtained by reacting 3,6-diamino-4-bromopiperidine with carbon dioxide under alkaline conditions.Safety Information:- Avoid direct contact with skin and eyes and wear appropriate personal protective equipment during handling.- When using or handling the compound, ensure that the operating environment is well ventilated to avoid inhalation or exposure to excessive dust or gas.- When storing and handling, the compound should be stored in an airtight container, away from ignition and flammable substances.
Application
4-Bromo-1,2-dihydropyridazine-3,6-dione (CAS 15456-86-7) is a specialized heterocyclic building block with a reactive bromine atom and two carbonyl groups on the pyridazine ring. It is widely utilized in drug discovery for synthesizing kinase inhibitors and anticancer agents, with studies showing activity against breast and colon cancer cell lines. In chemical biology, its bromine handle enables efficient cross-coupling reactions (Suzuki, Buchwald-Hartwig) to construct diverse 3-amino pyridazine libraries for SAR optimization. The compound also serves in bioconjugation strategies, forming cleavable linkages with cysteine residues in proteins for targeted therapy development. Additionally, it functions as an insecticide intermediate for crop protection agrochemicals. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this high‑purity scaffold with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.
