Pyrrole（CAS#109-97-7）
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Product Name and CAS Number
Pyrrole | CAS 109 97 7
One Line Sourcing Position
High purity Pyrrole for pharmaceutical synthesis, conducting polymer research, and specialty chemical applications.
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Specification
Purity by GC: 98.0 percent minimum, typical batch 98.5 to 99.0 percent
Appearance: Colorless to pale yellow to brownish liquid (darkens upon exposure to air)
Odor: Nutty, chloroform like, warm aromatic
Density at 20 deg C: 0.965 to 0.970 g per mL
Refractive index nD20: 1.508 to 1.510
Boiling point: 129 to 131 deg C
Water content Karl Fischer: 0.20 percent maximum
Assay by titration: 98.0 to 101.0 percent
Stabilizer: 0.05 to 0.10 percent BHT or hydroquinone (optional)
Stock Status: In Stock in US warehouse and China hub
Available Quantity and Lead Time
Regular supply: 500 g to 10 metric tons per shipment
Lead time: 3 to 5 days for standard packaging; bulk orders require 10 to 14 days
Document Support
COA SDS HPLC chromatogram NMR spectrum Mass spectrum MS available upon request
Application
Pyrrole is a fundamental heterocyclic compound that serves as a building block for numerous biologically active molecules and advanced materials. In pharmaceutical synthesis, the pyrrole ring is a key structural motif in drugs such as atorvastatin (Lipitor, a cholesterol lowering statin), sunitinib (anticancer), and various antibiotics (e.g., pyrrolnitrin, pyoluteorin). It is also used in the synthesis of porphyrins, heme analogs, and bile pigments. In materials science, pyrrole is the monomer for polypyrrole, an intrinsically conducting polymer used in antistatic coatings, corrosion protection, supercapacitors, sensors, and actuators. The compound is employed in the production of pyrrole based pharmaceuticals, agrochemicals (fungicides and insecticides), and photographic developers. In organic synthesis, pyrrole serves as a nucleophile in electrophilic substitution reactions (e.g., Vilsmeier Haack formylation, acylation, halogenation) and as a precursor for pyrrole carboxylic acids and pyrrole aldehydes. It is also used in the synthesis of calixpyrroles for anion recognition and supramolecular chemistry. Additionally, pyrrole finds application as a corrosion inhibitor in metalworking fluids and as an intermediate for flame retardants. In flavor and fragrance, trace amounts contribute nutty and ethereal notes.
Custom Synthesis Support
We offer custom synthesis for pyrrole derivatives including N alkylpyrroles, 2 acylpyrroles, pyrrole carboxylic acids, and substituted polypyrrole precursors. Share your technical datasheet for feasibility review.
Packaging and Shipping
Available in 500 mL, 1 L, 5 L, 25 L HDPE drums, or 200 L steel drums under inert atmosphere. Custom packaging such as amber glass ampoules with PTFE lined caps is supported. Fastest dispatch within 7 days after order confirmation. Pyrrole is a flammable liquid Class 3, UN 1994, PG II. Store in a cool, dark place under nitrogen. The compound darkens upon exposure to air; addition of stabilizer is recommended for long term storage.
Why XinChem
XinChem provides pyrrole with strict control of purity, water content, and oxidation products for US customers. Our ISO 9001 certified facility monitors every batch by GC and Karl Fischer analysis, ensuring consistent reactivity for pharmaceutical and polymer applications. We maintain a buffer stock of 2 metric tons in US warehouses for emergency deliveries within 48 hours. Each order includes a full documentation package: COA, SDS, GC chromatograms, and NMR spectra accessible through our online portal. Our technical support team assists with handling under inert atmosphere, stabilizer recommendations, and regulatory compliance including TSCA, EINECS, and DEA monitoring (where applicable). For contract customers, we offer quarterly price locks and consignment inventory to reduce supply chain risk. Trusted by over 120 pharmaceutical, polymer research, and fine chemical companies in North America. We also provide free sample evaluation for qualified R&D projects and a price match guarantee against any valid competitor quote for equivalent quality. Additionally, we offer custom stabilizer blends (BHT, hydroquinone, or other inhibitors) to suit your storage and handling requirements.
FAQ
Q1 How should pyrrole be stored to prevent degradation?
A Store in a cool, dark place under inert atmosphere (nitrogen or argon). Add stabilizer (e.g., BHT or hydroquinone) to inhibit polymerization. Keep container tightly sealed. Shelf life is 6 to 12 months under recommended conditions.
Q2 What purity grades do you supply?
A Standard grade is 98.0 percent by GC. We also supply 99.0 percent grade for pharmaceutical synthesis and electronic grade for conductive polymer research.
Q3 Is pyrrole soluble in water?
A Slightly soluble in water (about 6 g per 100 mL). Freely miscible with ethanol, diethyl ether, acetone, and most organic solvents.
Q4 Do you provide sample quantities for polymer research?
A Yes, free samples of 100 mL are available for qualified US companies. Shipping fee applies for small quantities.
Q5 What safety measures are required when handling pyrrole?
A Use in a fume hood with full PPE (gloves, goggles, lab coat). Pyrrole is toxic and may cause skin irritation. Avoid inhalation and prolonged exposure.
Q6 Can you supply pyrrole without any stabilizer for specific reactions?
A Yes, unstabilized pyrrole is available for immediate use. Please note that it must be used within a short time (days) under inert atmosphere. Custom stabilization levels are also offered.
Q7 What are common impurities in pyrrole and how do you control them?
A Key impurities include 2 methylpyrrole, pyrrolidine, and oligomers. Our specification limits each below 0.3 percent. Full impurity profile provided per batch.
