1-hydroxyhept-6-yn-3-one (CAS# 1450754-40-1)

Introduction

Toxin peptides are a class of toxic peptide molecules, usually produced by bacteria, plants, or animals. The properties of toxin peptides depend on their structure and source, and some are neurotoxic, cytotoxic, or otherwise biological. CALCISEPTINE IS A TOXIN PEPTIDE WITH CAS NUMBER 178805-91-9, AND ITS SPECIFIC PROPERTIES REQUIRE FURTHER INVESTIGATION.

The preparation of toxin peptides usually needs to be extracted from living organisms or obtained by synthetic methods, and the preparation process can be complex and requires professional technical support.

Toxin peptides are potentially toxic, and the dosage and concentration need to be strictly controlled when used to avoid harm to the human body or the environment. When operating in the laboratory, you need to wear personal protective equipment and follow the relevant safety operating procedures. For the research and application of toxin peptides, relevant regulations and safety standards should be followed to ensure the safety of people and the environment.

Application

1-Hydroxyhept-6-yn-3-one (CAS 1450754-40-1) is a high‑purity (≥95 %) research compound containing a terminal alkyne, a ketone, and a primary alcohol group. Its unique combination of a hydroxyl, a ketone, and an alkyne functionality makes it an extremely versatile intermediate in multistep organic synthesis. In medicinal chemistry, it is employed to construct a new class of diaziridine – containing building blocks for the synthesis of photocrosslinking probes and covalent inhibitors used to study protein interactions. The compound also serves as a key starting material for the synthesis of novel heterocyclic scaffolds (e.g., γ‑lactams, pyrrolidines, pyrazoles, isoxazoles) via propargylic substitutions, alkynylations and asymmetric reductions. Through reduction of the ketone, hydrogenation of the triple bond, or transformation of the hydroxyl group, it provides a direct route to functionalized diols, chiral alcohols and amino alcohol derivatives that are common pharmacophores in drug discovery programs. Furthermore, the presence of the terminal alkyne enables Sonogashira cross‑coupling and “click”‑chemistry (CuAAC) to rapidly generate focused compound libraries for hit‑to‑lead optimization. Beyond pharmaceutical research, 1‑hydroxyhept‑6‑yn‑3‑one is utilized in the development of agrochemicals, advanced functional polymers, and specialty fine chemicals, where its structure can be tailored to specific applications. Xinchem offers custom synthesis, custom chemical synthesis and contract manufacturing of 1‑hydroxyhept‑6‑yn‑3‑one with global supply, scaled reliably from R&D gram quantities to commercial tons. Contact us today for a competitive quote and dependable global delivery.