2-Amino-3-bromopyridine(CAS#13534-99-1)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
| Packing Group | II |
Introduction
2-Amino-3-bromopyridine is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 2-amino-3-bromopyridine:Quality:- Appearance: 2-amino-3-bromopyridine exists in the form of white crystals or crystalline powders.- Solubility: Soluble in organic solvents such as ethanol and ether, insoluble in water.Use:- 2-Amino-3-bromopyridine is an important intermediate compound that is commonly used in organic synthesis.Method:- The preparation of 2-amino-3-bromopyridine is generally obtained by chemical synthesis. A commonly used synthesis method is preparation by the reaction of bromide and pyridine.Safety Information:- 2-Amino-3-bromopyridine may be toxic to the environment and pollution to the environment should be avoided.- Laboratory safety operating procedures should be followed when using or handling the compound.- 2-Amino-3-bromopyridine may be harmful to humans and should be carefully avoided in contact or inhalation. Appropriate personal protective equipment such as gloves and respiratory protection should be worn.- During storage and transportation, strict compliance should be made to avoid exposure to high temperatures, ignitions, or open flames.
Application
2-Amino-3-bromopyridine is a high-purity heterocyclic building block used in medicinal chemistry and pharmaceutical R&D. The bromine at C3 enables selective cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig), while the amino group allows amide formation and further functionalization. This scaffold is widely employed to synthesize potent kinase inhibitors (e.g., JAK, BTK, CDK) for targeted cancer therapy, as well as antiviral, antibacterial, and anti-inflammatory agents. Its rigid pyridine core improves metabolic stability and target affinity. It also serves as an intermediate for agrochemicals and functional materials. High purity ensures reproducible SAR studies and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 2-Amino-3-bromopyridine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
