2-BroMo-6,7-dihydro-4H-pyrano[4,3-d]thiazole(CAS#1093107-56-2)

Introduction

2-Bromo-6,7-dihydro-4H-pyrano[4,3-D]thiazole is an organic compound.Properties: 2-Bromo-6,7-dihydro-4H-pyrano[4,3-D]thiazole is a solid, usually light yellow to white crystalline substance. It is insoluble in water at room temperature but soluble in many organic solvents.It may be used as an intermediate in the synthesis of other organic compounds, and may also play a role in biomedical research.Method: The preparation method of 2-bromo-6,7-dihydro-4H-pyrano[4,3-D]thiazole may be complex and may depend on the specific research or application purpose.When handling this compound, common laboratory safety protocols should be followed, including wearing appropriate protective gear, avoiding inhalation, skin and eye contact, and proper disposal of waste. The toxicology and safety of the compound should be thoroughly evaluated prior to use.

Application
2-Bromo-6,7-dihydro-4H-pyrano[4,3-d]thiazole (CAS 1093107-56-2) is a versatile brominated bicyclic heterocycle used as a key pharmaceutical intermediate in medicinal chemistry. The bromine atom at the 2-position enables efficient palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig, Sonogashira) to rapidly introduce diverse aryl, heteroaryl, or alkyl substituents. Its rigid pyrano-thiazole core serves as a privileged scaffold for the synthesis of selective kinase inhibitors targeting cancer, inflammation, and autoimmune diseases (e.g., PI3K, CDK, and EGFR inhibitors). This building block also supports the development of antiviral, antibacterial, and antifungal agents. The dihydropyrano[4,3-d]thiazole system offers excellent metabolic stability and target binding affinity. High purity ensures reproducible results in high-throughput screening, structure-activity relationship (SAR) studies, and scalable GMP manufacturing. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this essential intermediate with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.