3 5-difluorobenzoic acid（CAS# 455-40-3)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 – Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29163990 |
| Hazard Class | IRRITANT |
Introduction
3,5-Difluorobenzoic acid is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:
Quality:
- 3,5-Difluorobenzoic acid is a colorless crystal or white crystalline powder.
- It is almost insoluble in water at room temperature, but soluble in organic solvents such as ethanol, ether, etc.
- The compound has a strong pungent odor and is corrosive.
Use:
- 3,5-Difluorobenzoic acid is mainly used as an important intermediate and reagent in organic synthesis.
- The compound can be used in the fluorination reaction and coupling reaction of aromatic compounds in organic synthesis reactions.
Method:
- The preparation method of 3,5-difluorobenzoic acid can be obtained by the reaction of benzoic acid and hydrofluoric acid in the presence of a catalyst.
- Under reaction conditions, benzoic acid is mixed with hydrofluoric acid and heated, and the reaction is carried out under the action of a catalyst to generate 3,5-difluorobenzoic acid.
Safety Information:
- 3,5-Difluorobenzoic acid is an irritating compound that can cause irritation in contact with the skin and eyes, and suitable personal protective equipment must be worn.
- Care should be taken to avoid contact with strong oxidizing agents and strong alkaline substances when using or storing this compound to prevent dangerous reactions.
- Avoid sniffing excessive vapor of 3,5-difluorobenzoic acid, as it has a pungent odor.
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