3-Bromo-5-fluoroindole(CAS#1186663-46-6)

 3-Bromo-5-fluoroindole(CAS#1186663-46-6)

Physical and chemical properties: usually solid, the specific melting point, boiling point, density and other data are not publicly available. As a halogenated aromatic heterocyclic compound, it can be speculated to have certain stability. It may be slightly soluble in water and easily soluble in some organic solvents, such as methylene chloride, N,N-dimethylformamide, dimethyl sulfoxide, etc.
Uses: It is an important intermediate in organic synthesis and has important applications in the field of medicinal chemistry. The bromine atom, fluorine atom and indole ring in its structure can be modified by various chemical reactions, so as to introduce different pharmacophores for the synthesis of compounds with potential biological activity, which may have antibacterial, antiviral, antitumor and other activities. In materials science, it is also possible to prepare organic materials with special properties, such as optoelectronic materials, through further derivatization reactions.
Synthesis method: Generally, fluoroaniline is used as the starting material, and it is synthesized through multi-step reaction. For example, fluoroaniline is reacted with the corresponding halogenated hydrocarbons, and then the target product is obtained through steps such as cyclization and bromination. However, the specific synthesis route may vary depending on the raw material and reaction conditions.