6-Aminoquinazoline(CAS#101421-72-1)

Introduction

6-Aminoquinazoline is an organic compound. The following describes their properties, uses, manufacturing methods and safety information:Quality:- 6-Aminoquinazoline is a white crystalline solid.- It is insoluble in water at room temperature, but soluble in a variety of organic solvents.- 6-Aminoquinazoline is a stable compound that is relatively stable to oxidation and light.- It has a neutral nature and does not have significant acidity and alkalinity.Use:- 6-Aminoquinazoline has a variety of applications.- In addition, it is also used as an organic luminescent material, dye intermediate, etc.Method:- 6-Aminoquinazoline can be prepared by the condensation reaction of acetic acid tablets with p-aminobenzaldehyde.- For specific preparation methods, please refer to organic synthesis literature or patents.Safety Information:- 6-Aminoquinazoline does not have obvious safety risks under normal conditions.- Like all chemicals, use with care for safe handling and avoid inhalation, contact with skin and eyes.- Appropriate personal protective measures such as gloves, goggles, and good ventilation should be taken during use.- It should be stored in a dry and cool place to avoid contact with substances such as oxidants to prevent accidents.

Application
6-Aminoquinazoline (CAS 101421-72-1) is a functionalized heterocyclic scaffold featuring an amino group at the 6-position of the quinazoline core. This building block is widely used in medicinal chemistry and drug discovery for the synthesis of potent tyrosine kinase inhibitors, particularly targeting EGFR, HER2, and VEGFR in non‑small cell lung cancer, breast cancer, and other malignancies. The amino group enables amide, urea, sulfonamide, or heterocycle formation, allowing rapid structure‑activity relationship (SAR) studies and the construction of diverse drug‑like libraries. It is also utilized in the development of antiviral, anti‑inflammatory, antimicrobial, and CNS‑active agents. High purity ensures reproducible results in high‑throughput screening and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high‑purity 6‑aminoquinazoline with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.