3-Oxo-cyclobutanecarboxylic acid(CAS#23761-23-1)
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. S60 - This material and its container must be disposed of as hazardous waste. |
| TSCA | No |
| HS Code | 29189900 |
Introduction
3-oxocyclobutane carboxylic acid is an organic compound.Quality:3-oxocyclobutyl carboxylic acid is a colorless to pale yellow liquid with a special fragrance. It can be dissolved in water at room temperature and has a certain corrosiveness.Use:3-oxocyclobutane carboxylic acid is mainly used in organic synthesis reactions. It can be used as an important intermediate for the synthesis of various organic compounds, such as nitrogenous compounds, oxygenated compounds, etc.Method:There are several ways to prepare 3-oxocyclobutane carboxylic acids. A common method is to react cyclobutanone with anhydride to produce 3-oxocyclobutyl carboxylic acid.Safety Information:3-oxocyclobutyl carboxylic acid is an organic compound that may be harmful to the human body and the environment. Appropriate precautions should be taken during use and handling, such as wearing protective eyewear, protective gloves and face shields. Avoid inhaling, swallowing, or touching skin. The compound should be properly stored and disposed of in accordance with the relevant safety operating procedures to prevent accidents.
Application
3-Oxocyclobutanecarboxylic acid is a highly strained, four-membered cyclic ketone acid that functions as a versatile pharmaceutical intermediate. It is widely utilized as a key building block in the synthesis of diverse drug targets, including JAK inhibitors, MDM2 antagonists, CETP inhibitors, PDE10 inhibitors, and kinase inhibitors for the treatment of autoimmune disorders, chronic inflammatory conditions, and solid tumors. Its rigid cyclobutane scaffold confers enhanced metabolic stability and binding entropy, making it valuable in medicinal chemistry for constructing conformationally constrained bioactive molecules. In materials science, it serves as an intermediate for organic light-emitting diodes (OLEDs). Xinchem offers reliable custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 3-Oxocyclobutanecarboxylic acid with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and global supply.



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