4-broMoquinolin-6-aMine(CAS#1260785-25-8)

Introduction

4-Bromoquinoline-6-amine is an organic compound. The following is an introduction to its nature, use, preparation and safety information:Quality:- Appearance: Colorless to pale yellow crystals- Relative molecular weight: 221.07 g/mol- Solubility: Soluble in most organic solvents, such as ethanol and dimethylformamideUse:- 4-Bromoquinoline-6-amine is an important intermediate compound that is often used in organic synthesis reactions.Method:- The preparation of 4-bromoquinoline-6-amine usually involves the reaction of 2-methylquinoline with bromide to produce brominated products, which are then reduced or aminolyzed to obtain the target product.Safety Information:- 4-Bromoquinoline-6-amine is less toxic, but safe handling is still important.- Wear appropriate protective equipment, such as protective gloves and goggles, when in contact.- Avoid inhaling its dust or gases and avoid contact with skin and eyes.- In case of accidental ingestion or contact, seek medical advice immediately and present the packaging container or safety data sheet.

Application
4-Bromoquinolin-6-amine (4-bromo-6-aminoquinoline, CAS 1260785-25-8) is a high-value brominated heterocyclic building block. In medicinal chemistry, its quinoline amine scaffold serves as a pivotal intermediate for developing antiparasitic and antimalarial drugs that interact with biological targets to inhibit pathogen growth. Researchers also utilize this versatile intermediate for the synthesis of anticancer agents, leveraging its ability to effectively engage biological targets, and for developing kinase inhibitors such as EGFR-TK inhibitors. In the pharmaceutical industry, it functions as a crucial precursor for constructing bioactive molecules targeting infectious diseases and antipsychotic agents. It is also employed in the synthesis of coordination polymers and in various biochemical assays for studying enzyme activities. With the bromine atom enabling cross-coupling reactions and the amino group allowing further functionalization, 4-bromoquinolin-6-amine provides excellent synthetic versatility for rapid SAR studies. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this pharmaceutical intermediate with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.