4-Chloro-1H-pyrazolo[3,4-d]pyrimidine(CAS#5399-92-8)

Introduction

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine is an organic compound with the chemical formula C5H2ClN5. The following is a description of its nature, use, formulation and safety information:

Nature:

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine is a white crystalline solid, soluble in organic solvents such as chloroform and dimethyl sulfoxide. It decomposes at high temperatures and can undergo violent reactions, so it needs to be treated under cooling conditions.

Use:

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine is widely used in organic synthesis, especially in the field of drug synthesis. It is an important intermediate for the synthesis of various pyrazolo [3,4-d] pyrimidine derivatives, which have antitumor, antiviral and antibacterial activities.

Preparation Method:

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine was synthesized by a multi-step reaction starting from 4-chloro-pyrimidine. The specific method will vary according to the needs and conditions of the laboratory, generally including catalytic hydrogenation, azide treatment, hydrogenation reduction and other steps.

Safety Information:

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine can be used relatively safely under correct operating conditions. However, it is an organic compound and requires appropriate protective measures, such as wearing laboratory gloves, eye and respiratory protection equipment. In addition, it should avoid contact with oxidants and strong acids to prevent unsafe chemical reactions. During handling and storage, relevant safe operating procedures shall be followed. If ingested or inhaled, seek medical attention immediately.