4-Chloro-2-fluoroaniline(CAS#57946-56-2)
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2810 |
| WGK Germany | 3 |
| HS Code | 29214200 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | III |
Introduction
4-Chloro-2-fluoroaniline is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:Quality:- 4-Chloro-2-fluoroaniline is a colorless to yellowish solid with a peculiar odor.- At room temperature, it can be soluble in organic solvents such as alcohols, ethers, and methylene chloride.- This compound is stable and can be used under routine experimental conditions.Use:- 4-Chloro-2-fluoroaniline can be used as a starting substance in organic synthesis. It can undergo different reaction pathways to further convert into other compounds.- It is also used as a synthetic intermediate for dyes and pigments.Method:- A common method for the preparation of 4-chloro-2-fluoroaniline is by fluorination and chlorination.Safety Information:- 4-Chloro-2-fluoroaniline should be handled with care and avoid inhalation, ingestion, or skin contact.- When operating, safety measures should be followed, protective gloves, glasses should be used, and good ventilation should be provided outside the laboratory.- If any exposure or inhalation of this compound causes discomfort, medical attention should be sought immediately.
Application
4-Chloro-2-fluoroaniline (CAS 57946-56-2) is a halogenated aromatic amine widely used as a versatile pharmaceutical intermediate in API synthesis, particularly for quinazoline derivatives and antimicrobial agents. It serves as a key building block in the production of herbicides, including the novel protoporphyrinogen oxidase (PPO) inhibitor tiafenacil, as well as in the development of fungicides, insecticides, and organic synthesis intermediates. Its unique electronic properties enable applications in liquid crystal materials for display technologies and as a synthetic intermediate for dyes and pigments. The compound’s reactivity facilitates custom chemical synthesis of complex molecules for drug discovery and agrochemical R&D. Xinchem offers high‑purity 4-Chloro-2-fluoroaniline with flexible custom synthesis, custom chemical synthesis, and contract manufacturing, reliably scaled from R&D to commercial production. Contact us for a competitive quote and global supply.
