4-Chloro-2-nitroanisole（CAS# 89-21-4)
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37 - Wear suitable gloves. |
| HS Code | 29093090 |
Introduction
4-Chloro-2-nitroanisole. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
- Appearance: 4-Chloro-2-nitroanisole is a liquid, colorless or light yellow.
- Solubility: It is soluble in organic solvents such as ethers, alcohols, and chlorinated hydrocarbons.
Use:
- Explosives: 4-chloro-2-nitroanisole is a high-energy explosive that is used as a major ingredient or additive in military and industrial applications.
- Synthesis: It is an important raw material for the synthesis of other compounds, such as synthetic dyes and the starting material of organic synthesis reactions.
Method:
- 4-Chloro-2-nitroanisole, usually obtained by chlorination and nitrification of nitroanisole. Nitroanisone is reacted with chlorine to form 4-chloronitroanisole, which is then purified to obtain the target product.
Safety Information:
- 4-Chloro-2-nitroanisole is a volatile and irritating compound and should be kept away from fire and high temperatures. Wear protective equipment, including gloves, goggles, and protective clothing.
- It has an irritating effect on the eyes, skin, and respiratory tract, avoid direct contact.
- If inhaled or ingested, seek immediate medical attention.
- Waste disposal should be carried out in accordance with local laws and regulations to avoid environmental pollution.
- Observe safe operating practices during use or storage to ensure proper ventilation conditions.
Application
4-Chloro-2-nitroanisole (CAS 89-21-4) is a versatile organic building block widely utilized as a chemical intermediate in pharmaceutical, agrochemical, and dye manufacturing. The molecule features reactive handles, including a chlorine atom and a nitro group, which enable selective nucleophilic aromatic substitution and reduction, making it a valuable precursor for various complex molecules.
In the pharmaceutical industry, it is a key intermediate for the synthesis of active pharmaceutical ingredients (APIs) and other therapeutic agents. Its derivatives have shown potential for the development of new drugs to treat infectious diseases. In agrochemicals, 4-chloro-2-nitroanisole serves as a crucial building block for herbicides, fungicides, and insecticides. It is also used in the dye industry to produce various colorants, including azo dyes. Furthermore, this compound is employed in materials science and as a precursor for organic synthesis reactions. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 4-Chloro-2-nitroanisole with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.
