4-Chloronicotinic acid(CAS#10177-29-4)
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | IRRITANT, KEEP COLD |
| Packing Group | III |
Introduction
4-Chloronicotinic acid, also known as 4-chloropyridine-2,6-dicarboxylic acid, is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 4-chloronicotinic acid:Quality:- 4-Chloronicotinic acid is a colorless crystalline powder with a peculiar bitter and sour taste.- It dissolves slightly in water and is more soluble in organic solvents.- 4-Chloronicotinic acid has some acidic properties and can react with alkali to form salts.- It is an unstable compound that readily decomposes by heat or reacts with oxygen.Use:- 4-Chloronicotinic acid is widely used in organic synthesis and is often used as a catalyst or reaction intermediate.- It can be used in the preparation of various chemicals such as glyphosate (a herbicide), dyes, preservatives, etc.Method:- 4-Chloronicotinic acid can be prepared in a variety of ways. The commonly used method is obtained by chlorination of pyridine-2,6-dicarboxylic acid, or by alkali-catalyzed carboxylation of 3,5-dichloropyridine.Safety Information:- 4-Chloronicotinic acid is an organic compound that is toxic.- Contact with the skin or inhalation of its dust may cause health problems such as irritation, allergies, or respiratory discomfort.- Wear personal protective equipment when using or handling 4-chloronicotinic acid and avoid direct contact and inhalation.- When storing and handling 4-chloronicotin, the necessary safety measures should be taken, including keeping away from fire sources and accompanying ventilation equipment.
Application
Methyl 4‑methoxynicotinate (CAS 10177‑32‑9) is a versatile pyridine‑based building block that serves as a key pharmaceutical intermediate and research chemical. As a nicotinic acid derivative, its unique 4‑methoxy substitution pattern provides distinct reactivity for constructing complex heterocycles, nitrogen‑containing drug candidates, and agrochemicals. The methyl ester facilitates selective functionalization, making this compound an ideal synthetic intermediate for preparing kinase inhibitors, GPCR modulators, and anti‑inflammatory agents. Ongoing research also highlights its potential antimicrobial and antioxidant properties. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high‑purity methyl 4‑methoxynicotinate with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
