5-Bromo-2-fluorobenzyl alcohol CAS 99725-13-0
Introduction
Toxin peptides are a class of toxic peptide molecules, usually produced by bacteria, plants, or animals. The properties of toxin peptides depend on their structure and source, and some are neurotoxic, cytotoxic, or otherwise biological. CALCISEPTINE IS A TOXIN PEPTIDE WITH CAS NUMBER 178805-91-9, AND ITS SPECIFIC PROPERTIES REQUIRE FURTHER INVESTIGATION.
The preparation of toxin peptides usually needs to be extracted from living organisms or obtained by synthetic methods, and the preparation process can be complex and requires professional technical support.
Toxin peptides are potentially toxic, and the dosage and concentration need to be strictly controlled when used to avoid harm to the human body or the environment. When operating in the laboratory, you need to wear personal protective equipment and follow the relevant safety operating procedures. For the research and application of toxin peptides, relevant regulations and safety standards should be followed to ensure the safety of people and the environment.
Application
5-Bromo-2-fluorobenzyl alcohol (CAS 99725-13-0) is a versatile halogenated benzyl alcohol serving as a key building block in pharmaceutical and agrochemical research. Its reactive primary alcohol group enables facile oxidation to the corresponding aldehyde or carboxylic acid, as well as esterification and ether formation, allowing rapid diversification. The orthogonal halogen handles (bromine and fluorine) provide sites for regioselective palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig, Sonogashira) and nucleophilic aromatic substitution, facilitating the construction of complex molecular scaffolds. This intermediate is widely utilized in medicinal chemistry for the synthesis of kinase inhibitors, antiviral agents, and central nervous system (CNS) drug candidates, where the bromo-fluoro substitution pattern enhances metabolic stability and target binding affinity. In agrochemical development, it serves as a core precursor for selective herbicides, fungicides, and insecticides with improved environmental profiles. Its high purity ensures reproducible results in structure-activity relationship (SAR) studies, high-throughput screening, and scalable GMP manufacturing for pharmaceutical, agrochemical, and fine chemical applications. Xinchem offers custom synthesis and contract manufacturing of this essential building block with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.
