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5-Methoxyindole(CAS#1006-94-6)

Chemical Property:

Molecular Formula C9H9NO
Molar Mass 147.17
Density 1.1135 (rough estimate)
Melting Point 52-55 °C (lit.)
Boling Point 176-178 °C/17 mmHg (lit.)
Flash Point 176-178°C/17mm
Water Solubility insoluble
Solubility Chloroform, Methanol
Vapor Presure 0.00234mmHg at 25°C
Appearance White crystal
Color White to light brownish
BRN 116722
pKa 16.70±0.30(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Sensitive Light Sensitive
Refractive Index 1.5310 (estimate)
MDL MFCD00005674
Physical and Chemical Properties Melting point 56-58°C
boiling point 176-178°C (17 mmHg)
water-soluble insoluble
Use Used as a pharmaceutical Intermediate

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
S24/25 – Avoid contact with skin and eyes.
S37/39 – Wear suitable gloves and eye/face protection
WGK Germany 3
RTECS NL9500000
FLUKA BRAND F CODES 8
HS Code 29339900
Hazard Note Irritant
Hazard Class IRRITANT, KEEP COLD,

 

Introduction

5-Methoxyindole is an organic compound. The following is a brief introduction to the properties, uses, preparation methods and safety information of 5-methoxyindole:Quality:- Appearance: 5-Methoxyindole is a white to light yellow crystal or crystalline powder.- Solubility: soluble in common organic solvents, such as ethanol, dimethylformamide, etc.Use:- Natural product synthesis: 5-methoxyindole can be used as an intermediate in the synthesis of natural products such as plant alkaloids.Method:The main methods for the synthesis of 5-methoxyindole are as follows:- Pyran method: pyran and sodium ethanol are used as raw materials to react under alkaline conditions to obtain 5-methoxyindole.- Functionalized substitution: Methoxy groups are introduced into the 5th position of the indole by methoxylating the indole compound.Safety Information:5-Methoxyindole has no reported toxicity and danger under normal conditions of use. As an organic compound, the following safety precautions should still be paid attention to when using:- Avoid contact with skin and eyes, and avoid inhaling their dust or gases.- Wear appropriate personal protective equipment (PPE) such as lab gloves and goggles when operating.- Operate under closed ventilation conditions to avoid the generation of harmful gases.- Waste should be disposed of in accordance with local regulations to avoid environmental pollution.


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