5-Methyl-2(1H)-pyrazinone(CAS#20721-17-9)
Introduction
5-Methyl-2(1H)-pyrazinone) is an organic compound with a chemical structure of a combination of pyrazine and hydroxyl groups.Quality:- Appearance: White crystalline solid- Soluble: Soluble in water and some organic solventsUse:- As a solvent: It has good solubility and can be used as a medium for dissolving and extracting solutes.Method:The preparation methods of 2-hydroxy-5 methylpyrazine are mainly as follows:- Condensation of pyrazine and ketone: Pyrazine is reacted with ketones to form a target product through a condensation reaction.- Oxidation of pyrazine: oxidizing pyrazine with an oxidant to generate 2-hydroxy-5 methylpyrazine.Safety Information:There are few toxicity and safety data for 2-hydroxy-5 methylpyrazine, and laboratory and operational practices need to be followed when using it.- As a chemical, it needs to be stored in a dry, cool, well-ventilated environment.- When operating, contact with the skin, eyes and mouth should be avoided, and appropriate personal protective equipment should be worn.- Seek immediate medical attention if ingestion, inhalation, or skin-to-skin contact occurs.
Application
5-Methyl-2(1H)-pyrazinone (CAS 20721-17-9) is a heterocyclic pyrazinone derivative with a characteristic nutty, roasted, cocoa-like aroma. In the flavor and fragrance industry, it serves as a high-impact flavoring agent (FEMA 3309) to impart roasted, nutty, and cocoa notes to baked goods, confectionery, dairy products, and beverages. As a versatile building block, it is widely used in medicinal chemistry for the synthesis of bioactive molecules, including kinase inhibitors, antiviral agents, and antimicrobial compounds. Its pyrazinone core provides hydrogen bond donor/acceptor sites, enhancing target binding affinity. The compound also serves as a key intermediate in the preparation of pharmaceutical candidates targeting neurological disorders and metabolic diseases. High purity ensures reproducible results in drug discovery and scalable GMP synthesis. Xinchem offers custom synthesis and contract manufacturing of this high-purity pyrazinone with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
