2-Hydroxy-6-methylpyrazine(CAS#20721-18-0)
2-Hydroxy-6-methylpyrazine(CAS#20721-18-0)
Uses: It is a useful synthesis intermediate that can be used in the synthesis of 2-hydroxy-3-phenyl-6-methylpyrazine. In addition, it is a fluorescent degradation product of the antibiotic cephalexin, which can be used for the determination of this antibiotic in aqueous solutions and human plasma.
Safety Information: Signal words are warnings, and hazard statements include H302 (harmful to swallowing), H315 (causing skin irritation), H319 (causing severe eye irritation), H335 (may cause respiratory irritation). Precautionary statements include P261 (avoid inhaling dust/fumes/gases/fumes/vapors/sprays), P305 P351 P338 (in case of contact with eyes: rinse carefully with water for a few minutes.) If you wear contact lenses and can easily remove them, remove them. Continue rinsing).
Application
2-Hydroxy-6-methylpyrazine (6-methylpyrazin-2-ol, CAS 20721-18-0) is a key heterocyclic intermediate used in pharmaceutical R&D, fine chemical synthesis, and agrochemical development. It acts as a precursor for 2-hydroxy-3-phenyl-6-methylpyrazine, a fluorescent degradation marker of cephalexin for quantifying this antibiotic in human plasma and aqueous solutions. The scaffold has also shown antimicrobial activity against Enterococcus faecium and inhibits L1210 leukemia cell viability, supporting antitumor research. Beyond bioactivity, it stabilizes formulations as an antioxidant. In agrochemicals, it serves as a core scaffold for potent fungicides and herbicides, improving crop protection and yields. Its unique pyrazine structure makes it a versatile building block for complex heterocycles, fluorescent probes, and advanced materials. Xinchem offers high‑purity product supported by complete CofA, HPLC, and MSDS, with flexible custom synthesis and contract manufacturing scaling from R&D to commercial tons. Contact us today for a competitive quote and global supply.
