6-Methylpyridazin-3(2H)-one(CAS#13327-27-0)
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37 - Wear suitable gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
Application
6-Methylpyridazin-3(2H)-one (CAS 13327-27-0) is a versatile pyridazinone heterocycle widely used as a key intermediate in pharmaceutical and agrochemical research. Its lactam-lactim tautomerism provides hydrogen bond donor/acceptor sites, making it a privileged scaffold for developing bioactive molecules. Derivatives exhibit potent anti-inflammatory, anticancer (e.g., CDK and kinase inhibitors), antimicrobial, and antihypertensive activities. The methyl group at the 6-position allows further functionalization via cross-coupling or electrophilic substitution, enabling rapid SAR studies. This building block is also utilized in the synthesis of herbicides, fungicides, and fluorescent probes. High purity ensures reproducible results in high-throughput screening and scalable GMP manufacturing. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this compound with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
