7-Nitroisoquinoline(CAS#13058-73-6)

Introduction

7-Nitroisoquinoline is an organic compound with the chemical formula C9H5N3O2. The following is a description of its nature, use, preparation and safety information:

Nature:

-7-Nitroisoquinoline is a pale yellow to yellow solid.

-It has strong oxidizing and explosive properties.

-Melting point is about 233-234°C.

Use:

-7-Nitroisoquinoline is an important additive for explosives and fuels.

-It can be used to prepare high-performance explosives, such as TNT (trinitrotoluene) and RDX (hexanitrodiisocyanate).

- 7-nitroisoquinoline can also be used in the preparation of photosensitive materials, dyes and munitions.

Preparation Method:

-7-nitroisoquinoline has many preparation methods, one of which is commonly used by the nitration of 2-nitroisoquinoline.

-The specific preparation method involves a multi-step reaction and requires precise operation and safety measures.

Safety Information:

-7-Nitroisoquinoline is a toxic and explosive compound.

-Strict safety procedures must be followed during handling and storage.

-Avoid inhalation, ingestion, or contact with skin and eyes, and wear appropriate personal protective equipment.

-When handling or storing this compound, keep it away from flammable materials, heat sources and open flames.

Please note that since 7-nitroisoquinoline is a hazardous substance, the specific experimental operation and use should be carried out in a professional laboratory environment and strictly comply with relevant safety regulations.

Application
7-Nitroisoquinoline (CAS 13058-73-6) is a functionalized heterocyclic building block widely used in medicinal chemistry and pharmaceutical research. The nitro group at the 7-position can be reduced to an amino group, enabling further derivatization via amide, urea, or sulfonamide formation. This scaffold serves as a key intermediate for the synthesis of kinase inhibitors, antimalarial agents, and phosphodiesterase (PDE) modulators targeting cancer, inflammation, and infectious diseases. It also facilitates the construction of isoquinoline-based ligands for CNS drug discovery. High purity ensures reproducible results in SAR studies and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 7-nitroisoquinoline with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.