Acetylleucine（CAS# 99-15-0)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29241900 |
Introduction
Acetylleucine is an unnatural amino acid also known as Acetyl-L-methionine.
Acetylleucine is a bioactive compound that has the effect of promoting protein synthesis and cell growth. It has potential benefits for improving animal performance and is widely used as an animal nutrition enhancer.
The preparation method of acetylleucine is mainly obtained by the reaction of ethyl acetate and leucine. The preparation process includes steps such as esterification, hydrolysis, and purification.
Safety Information: Acetylleucine is safe and non-toxic to humans and animals at general dosages. High doses of acetylleucine may cause some digestive discomfort symptoms such as nausea, vomiting, etc. Use in accordance with the directions for use, discontinue use immediately and consult a physician if any discomfort occurs. It should be stored in a dry, cool place to avoid contact with harmful substances.
Application
Acetylleucine (N-Acetyl-DL-leucine, CAS 99-15-0) is an orally active N-acetylated amino acid derivative used as a pharmaceutical intermediate and research compound for neurological disorders. As a drug substance, it is indicated for the symptomatic treatment of acute vestibular vertigo, dizziness, cerebellar ataxia, and nystagmus. The L-enantiomer (N-acetyl-L-leucine) is the bioactive isomer that accelerates vestibular compensation, potentially by restoring membrane potential through interaction with phospholipids on injured vestibular neurons. In pharmaceutical R&D, acetylleucine serves as a building block for peptide synthesis and other bioactive compounds. It is also used as an analytical reference standard for method development and quality control. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity acetylleucine (≥99%) with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.
