Isoquinoline, 7-(bromomethyl)- (9CI)(CAS#158654-75-2)
Introduction
7-(bromomethyl)isoquinoline is an organic compound. It is a derivative of isoquinoline and has a bromomethyl group in structure. The following is an introduction to its nature, use, manufacturing methods and safety information:Quality:- Appearance: 7-(bromomethyl)isoquinoline is a yellow to brown crystalline solid.- Solubility: Soluble in organic solvents (e.g., ethanol, dimethylformamide and methylene chloride) and slightly soluble in water.Use:- 7-(bromomethyl)isoquinoline can be used as an intermediate in organic synthesis for the synthesis of other organic compounds.Method:- 7-(bromomethyl)isoquinoline can be obtained by reacting isoquinoline with methyl bromide. The specific reaction conditions can be optimized according to the experimental needs.Safety Information:- 7-(bromomethyl)isoquinoline is an organic compound that poses certain potential safety risks and should be handled in a suitable laboratory environment.- When using or handling the compound, follow safe handling protocols, including wearing appropriate personal protective equipment (e.g., lab gloves, protective glasses, and lab clothing).- The compound should be stored in an airtight container and placed in a cool, dry place, away from fire and flammable substances.- When disposing of waste, it should be disposed of in accordance with local regulations to ensure environmental safety.
Application
7-(Bromomethyl)isoquinoline is a high-purity alkylating agent used as a key synthetic intermediate and versatile building block for complex heterocycles. It is highly valued in drug discovery for constructing pharmaceutical libraries, particularly as a precursor for TRPC6 inhibitors, which are novel therapeutic candidates for pain and hypertension. Its reactive bromomethyl group readily participates in cross-coupling reactions and nucleophilic substitutions, enabling the synthesis of targeted anticancer and antimicrobial agents. It is also employed to develop fluorescent probes for bioimaging and to fabricate organic electronics such as OLEDs. Xinchem provides 7-(Bromomethyl)isoquinoline with global custom chemical synthesis and contract manufacturing, ensuring scalable production from R&D to commercial tons. Contact us for a competitive quote and reliable supply.


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