morpholinecarboximidamide(CAS#5638-78-8)

Introduction

morpholine-4-carboximidamide(morpholine-4-carboximidamide) is an organic compound. It has a chemical formula of C, H, N · HCl and can form a white crystalline powder. The following is an introduction to its properties, applications, preparation methods and safety information:

Nature:

-Appearance: White crystalline powder.

-Melting point: about 170-180 ° C.

-Solubility: high solubility in water, soluble in many organic solvents.

Use:

-Chemical reagent: used as a reagent for the synthesis of certain raw materials and intermediates.

-Organic synthesis: It can be used as a catalyst or reagent in many organic synthesis reactions.

-Pharmaceutical field: as an intermediate for certain drugs.

Method:

morpholine-4-carboximidamide can be prepared by the following methods:

1. Morpholine is reacted with a certain amount of formamidine to obtain morpholine-4-formamidine.

2. Reacting morpholine-4-formamidine with hydrochloric acid to obtain morpholine-4-carboximidamide.

Safety Information:

morpholine-4-carboximidamide there is no clear risk information report. However, when using any chemical substance, it is necessary to follow safe operating guidelines, such as wearing appropriate protective equipment, avoiding inhalation, contact with skin and eyes, and avoiding ingestion. In the event of an accident, medical help should be sought immediately.

Please note that the information provided here is for informational purposes only and is not a substitute for actual chemical laboratory practice and professional safety guidance. Before using this compound, it is recommended to refer to its safety data sheet (SDS) for more detailed and accurate safety information.

Application

Morpholine-4-carboximidamide hydrochloride (CAS 5638-78-8) is a highly versatile carboximidamide-functionalized morpholine building block. Acting as a guanidine bioisostere, its unique structure allows interactions with enzyme active sites. It shows significant potential as an enzyme inhibitor for metabolic disorders and infectious diseases, and serves as a precursor for antiviral agents, including Moroxydine analogs, targeting influenza and other viral targets. In pharmaceutical R&D, it is used to synthesize heterocyclic compounds such as triazine derivatives with PDE4 inhibitory activity for respiratory diseases. This building block is also utilized in agrochemical development for new fungicides and herbicides, as well as in materials science for perovskite solar cells and CO₂ capture systems. Its water solubility and dual nucleophilic/electrophilic sites enable efficient incorporation into complex drug-like scaffolds via condensation and substitution reactions. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of morpholine-4-carboximidamide hydrochloride with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.