(S)-(-)-1-Phenylethylamine(CAS#2627-86-3)
Brief introduction
S(-)-α-methylbenzylamine is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of S(-)-α-methylbenzylamine:
1. Properties:
- Appearance: Colorless liquid or crystal.
- Odor: Has a special smell of ammonia and benzene.
- Density: Approximately 1.01 g/mL.
2. Usage:
- Catalyst: Can be used as a catalyst for organic synthesis reactions.
- Flame retardant: Can be used as a flame retardant to reduce the combustion properties of materials.
- Chemical Intermediates: Can be used as intermediates in the preparation of other compounds.
3. Preparation method:
- S(-)-α-methylbenzylamine can be prepared by reacting benzyl aluminane with methylamine.
- The preparation reaction is: benzyl aluminane methylamine → S(-)-α-methylbenzylamine.
4. Safety Information:
- S(-)-α-methylbenzylamine is irritating and should be avoided when it comes into contact with the skin and eyes.
- During use or storage, necessary safety measures should be taken to avoid inhalation, ingestion, and contact.
- Keep away from fire sources and oxidizing agents to prevent fires and explosions.
Before using or operating S(-)-α-methylbenzylamine, it is important to understand its properties and safety information in detail: and take appropriate protective measures according to the specific situation.
Application
(S)-(-)-1-Phenylethylamine (CAS 2627-86-3) is a widely used chiral building block and resolving agent in asymmetric synthesis. Its primary application is in the resolution of racemic carboxylic acids, phosphonic acids, and sulfonic acids via diastereomeric salt formation, enabling the production of enantiomerically pure pharmaceutical intermediates. It is also employed as a chiral auxiliary for the synthesis of β-lactams, amino acids, and other bioactive compounds. In the pharmaceutical industry, it serves as a key intermediate for the production of various drugs, including those for neurological disorders and antibiotics. Additionally, it is used in the synthesis of chiral ligands for asymmetric catalysis, such as in hydrogenation and cross-coupling reactions. Its high optical purity is critical for achieving desired stereochemical outcomes. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity (S)-(-)-1-phenylethylamine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
