SYN-AKE(CAS#823202-99-9)

Brief introduction
Snake venom tripeptides refer to a class of compounds that have a hormonal effect similar to that found in snake venom. Snake venom tripeptide can regulate cellular function by mimicking the corresponding natural hormone structure and binding to the receptors of the target cell.

Many of the active ingredients in snake venom are snake venom tripeptides like snake venom, colchicine, etc. These snake-like venom tripeptides can regulate physiological processes at the cellular level, such as neurotransmission, vasoconstriction, immune response, etc.

At present, many snake venom tripeptides have been applied in medical research and clinical treatment. They may have a variety of biological activities such as anti-inflammatory, analgesic, antitumor, antithrombosis, and hypotensive. The research on snake venom tripeptide is still in its early stages, and further research and verification of its potential and safety in clinical application are needed.

Application

SYN-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate, CAS 823202-99-9) is a synthetic tripeptide that mimics the mechanism of Waglerin-1, a peptide found in temple viper venom. As a reversible antagonist of the muscle nicotinic acetylcholine receptor (mnAChR), it blocks acetylcholine-mediated depolarization and subsequent muscle contraction, effectively relaxing facial muscles to reduce expression lines such as crow‘s feet, forehead wrinkles, and laugh lines. This “Botox-like” effect is fully reversible and does not compromise natural facial expressiveness. Clinical studies demonstrate that SYN-AKE significantly improves skin smoothness, reduces wrinkle depth, and enhances elasticity—with up to a 52% reduction in wrinkle severity after 28 days of use. The peptide also exhibits antioxidant activity, scavenging free radicals that contribute to skin aging. SYN-AKE is widely incorporated into premium anti-aging formulations including eye creams, serums, facial masks, lotions, and neck care products at recommended use levels of 0.05%–0.5%. It is stable, fast-acting, long-lasting, and compatible with various cosmetic formulations. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity SYN-AKE (≥98%), with flexible scaling from R&D samples to commercial tons, supported by comprehensive regulatory documentation. Contact us today for a competitive quote and reliable global supply.