2,3,4-trifluorotoluene(CAS#193533-92-5)
| Hazard Symbols | F - Flammable |
| Risk Codes | 10 - Flammable |
| Safety Description | 16 - Keep away from sources of ignition. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| Hazard Note | Flammable |
| Hazard Class | 3 |
| Packing Group | III |
Introduction
2,3,4-trifluorotoluene, also known as 2,3, 4-trifluorobenzene, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,3,4-trifluorotoluene is a colorless liquid.
-Melting point:-35 ℃
-Boiling point: 113 ℃
-Density: 1.542g/cm³
-Solubility: 2,3,4-trifluorotoluene has good solubility, soluble in alcohols, ethers and benzene solvents, but insoluble in water.
Use:
- 2,3,4-trifluorotoluene is mainly used as an important intermediate in organic synthesis.
-It can be used to synthesize compounds such as drugs, pesticides, dyes and high-performance polymers.
-It can also be used as an additive for coatings, solvents and surfactants.
Method:
- 2,3,4-trifluorotoluene is mainly prepared by the fluorination reaction of olefins.
-A typical preparation method is to fluorinate benzene and fluorine gas in the presence of a catalyst.
Safety Information:
- 2,3,4-trifluorotoluene is an organic compound with certain toxicity.
-use should be careful to avoid inhalation, contact with skin and eyes.
-It should be stored in a dark, dry and well-ventilated place.
-When handling and storing this compound, safe operating procedures must be followed and appropriate personal protective equipment must be worn.
-If inhaled or exposed to 2,3,4-trifluorotoluene, please wash it immediately and seek medical help if necessary.
When using and storing, be sure to ensure safety and follow relevant safety procedures. It is recommended to use 2,3,4-trifluorotoluene under the guidance of professionals.
Application
2,3,4-Trifluorotoluene (CAS 193533-92-5) is a key fluorinated aromatic intermediate in the synthesis of modern pharmaceuticals, including anti-inflammatory drugs (celecoxib, rofecoxib), antipsychotics, antidepressants, and antiviral agents. Its trifluoromethyl-substituted structure enhances metabolic stability, bioavailability, and biological activity, making it a valuable building block in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases. In agrochemical R&D, it serves as a core precursor for selective herbicides, pesticides, and fungicides, improving target selectivity and environmental profiles. Additionally, it functions as a specialty organic solvent, a monomer for fluorinated polymers, a precursor for liquid crystal displays (LCDs) and OLED components, and a reagent for novel cross-coupling methodologies. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 2,3,4-Trifluorotoluene with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
