2,4-Difluoro-3,5-dichloroaniline(CAS#83121-15-7)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Irritant |
Introduction
2,4-Difluoro-3,5-dichloroaniline is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:Quality:- Appearance: Colorless crystalline solid- Solubility: Slightly soluble in water, soluble in organic solvents such as ether and acetoneUse:- It can also be used as a catalyst or ligand in organic synthesis reactions, such as fluorination and chlorination.Method:- 2,4-Difluoro-3,5-dichloroaniline can be obtained by reacting 2,4-difluoronitrobenzene with hydrochloric acid to obtain 2,4-difluoro-3,5-dichloronitrobenzene. 2,4-Difluoro-3,5-dichloronitrobenzene was reduced to 2,4-difluoro-3,5-dichloroaniline.Safety Information:- 2,4-Difluoro-3,5-dichloroaniline poses a certain risk to the environment, and care should be taken to avoid it entering water sources and soils.- Appropriate precautions should be taken during use or handling to avoid contact with skin, eyes, and respiratory tract.- This compound can be toxic to the human body and may cause damage to the central nervous system, liver and kidneys.- During storage and handling, relevant safety operating procedures need to be adhered to to ensure safe use and management.
Application
2,4-Difluoro-3,5-dichloroaniline (CAS 83121-15-7) is a key halogenated aniline building block serving as the critical intermediate for the synthesis of Teflubenzuron, a potent benzoylphenylurea insecticide that disrupts chitin synthesis in target pests. As a versatile agrochemical intermediate, it enables the production of selective herbicides and fungicides through the construction of pyrimidine, pyrazole, and triazole active ingredients, effectively protecting cereal, rice, and soybean crops. In pharmaceutical research, its halogenated scaffold facilitates the development of antifungal, antiviral, and anti-inflammatory drug candidates. The compound also serves as a valuable precursor for azo dyes, anthraquinone dyes, and high-performance polymers, where the halogen substituents enhance thermal stability and color properties. Its versatile aniline functionality enables diazotization, cross-coupling, and electrophilic substitution transformations for rapid SAR exploration. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 2,4-Difluoro-3,5-dichloroaniline with flexible scaling from R&D grams to commercial metric tons, supported by comprehensive batch-specific COA and regulatory documentation. Contact us for a competitive quote and reliable global supply.
