page_banner

product

3,5-dichloro-4-fluoroaniline(CAS#2729-34-2)

Chemical Property:


Product Detail

Product Tags

 

Introduction

3,5-dichloro-4-fluoroaniline is an organic compound with the chemical formula C6H4Cl2FN. The following is a description of the properties, uses, preparation and safety information of the compound:

 

Nature:

-Appearance: 3,5-dichloro-4-fluoroaniline is a colorless to light yellow crystalline solid.

-Solubility: It can be well dissolved in organic solvents, such as ethanol, methanol and dichloromethane.

-Melting point: The melting point of 3,5-dichloro-4-fluoroaniline is about 80-82 degrees Celsius.

 

Use:

-Chemical synthesis: 3,5-dichloro-4-fluoroaniline is a commonly used organic synthesis intermediate. It can be used to prepare other compounds, such as pesticides, dyes, pharmaceuticals and other organic synthetic compounds.

-Research use: The substance is also used as a reagent in scientific research.

 

Method:

The preparation method of-3,5-dichloro-4-fluoroaniline can be carried out by nitrous acid treatment in the presence of 4-fluoroaniline, and then introducing chlorine atoms under appropriate conditions through chlorination reaction.

 

Safety Information:

- 3,5-dichloro-4-fluoroaniline has certain biological toxicity, so necessary safety measures should be taken during handling and storage.

-In contact with the substance, should avoid direct inhalation of its gas or contact with its dust.

-Wear appropriate protective gloves, glasses and respiratory protection when using or handling the substance.

-When storing and handling the substance, it should be placed in a sealed container, away from fire and oxidizing agents.

Application
3,5-Dichloro-4-fluoroaniline (CAS 2729-34-2) is a versatile halogenated aniline building block widely used as a key pharmaceutical and agrochemical intermediate. In drug discovery, it serves as a precursor for the synthesis of various therapeutic compounds, including kinase inhibitors, antiviral agents, and antimicrobial drugs. In crop protection, this intermediate is essential for the production of high-value insecticides such as Teflubenzuron and Hexaflumuron, as well as herbicides and fungicides. Its unique substitution pattern, featuring two chlorine atoms and one fluorine atom, enables regioselective nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions for rapid structure-activity relationship (SAR) studies. Additionally, it is utilized in the synthesis of dyes, pigments, and specialty polymers. High purity ensures reproducible results in high-throughput screening and scalable GMP manufacturing. Xinchem offers reliable custom synthesis, custom chemical synthesis, and contract manufacturing of this essential building block with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.

 


  • Previous:
  • Next:

  • Write your message here and send it to us