3,5-Dichloropyridazine(CAS#1837-55-4)

Introduction

3,5-Dichloropyridazine is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 3,5-dichloropyridazine:Quality:- Appearance: 3,5-Dichloropyridazine is a colorless to light yellow crystalline or crystalline powder.- Solubility: It is slightly soluble in water and soluble in organic solvents (e.g., ethanol, ether).- Stability: It is a stable compound, but it degrades when exposed to light.Use:- 3,5-Dichloropyridazine is mainly used as an intermediate in organic synthesis. It can be used for the synthesis of important organic functional groups such as pyrazine.- It can also be used as a raw material for pesticides in the synthesis of insecticides, herbicides, fungicides, etc.Method:- 3,5-Dichloropyridazine is usually prepared by the reaction of pyridazine and chlorine. The specific steps are:1. Dissolve pyridazine in methylene chloride or chlorinated alkanes.2. Chlorine gas is introduced into the solution and the reaction is heated.3. After the reaction is completed, the reaction products are filtered and washed, and then purified by crystallization to obtain pure products.Safety Information:- 3,5-Dichloropyridazine is a harmful substance that may cause harm to human health.- When handling or storing, avoid contact with combustibles to prevent fire or explosion accidents.- When using or handling the compound, strictly follow the relevant safe operating procedures and handle and dispose of it in accordance with local regulations.

Application
3,5-Dichloropyridazine (CAS 1837-55-4) is a versatile heterocyclic building block widely used in pharmaceutical and agrochemical research. The two reactive chlorine atoms enable sequential nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig), allowing rapid construction of diverse pyridazine-based libraries. In medicinal chemistry, it serves as a key intermediate for synthesizing kinase inhibitors, antibacterial, antifungal, and antiviral agents. In crop protection, it is a crucial precursor for developing selective herbicides and fungicides with improved bioavailability and low environmental impact. Its derivatives also show potential in treating inflammatory diseases and central nervous system disorders. High purity ensures reproducible results in high-throughput screening and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 3,5-dichloropyridazine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.