4-Chloro-2-methylbenzoic acid(CAS#7499-07-2)
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29163990 |
| Hazard Class | IRRITANT |
Introduction
4-Chloro-2-methylbenzoic acid, chemical formula C8H7ClO2, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: about 143-145 degrees Celsius
-Solubility: Soluble in many organic solvents such as alcohols, ethers and chlorinated hydrocarbons
-Chemical properties: esterification reaction can occur in the presence of strong alkali, and react with some organic metals to generate corresponding metal salts
Use:
- 4-Chloro-2-methylbenzoic acid can be used as pharmaceutical and pesticide intermediates for the synthesis of other organic compounds
-can be used as a catalyst or reducing agent in some organic synthesis reactions
-Can be used to research and analyze certain reagents in chemistry
Preparation Method:
-The common preparation method is to chlorinate benzoic acid, and then alkylate the obtained product to obtain 4-Chloro-2-methylbenzoic acid
Safety Information:
- 4-Chloro-2-methylbenzoic acid is an organic compound, care should be taken to prevent direct contact with skin and eyes
-Avoid contact with oxidants and strong acids during use or storage
-For specific information on its toxicity and danger, consult relevant safety materials or professionals
Application
4-Chloro-2-methylbenzoic acid (CAS 7499-07-2) is a versatile halogenated benzoic acid derivative widely used as a key building block in pharmaceutical and agrochemical research. In drug discovery, it serves as an essential pharmaceutical intermediate for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), analgesic agents, and antimicrobial compounds, facilitating the construction of bioactive molecules through amide coupling and Friedel–Crafts acylation reactions. In agrochemistry, this compound functions as a core scaffold for the preparation of herbicides, fungicides, and insecticides, contributing to enhanced crop protection. It is also utilized in polymer chemistry as a monomer for specialty polymers and high-performance materials, and in the synthesis of dyes, pigments, and fine chemicals. With excellent solubility in organic solvents and high purity (≥98%), 4-Chloro-2-methylbenzoic acid is an indispensable tool for organic synthesis and analytical method development. Xinchem offers custom synthesis and contract manufacturing of this compound with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
