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5-amino-2-methyl benzoic acid(CAS#2840-04-2)

Chemical Property:

Molecular Formula C8H9NO2
Molar Mass 151.16
Density 1.254±0.06 g/cm3(Predicted)
Melting Point 194-199 °C
Boling Point 348.8±30.0 °C(Predicted)
Flash Point 164.7°C
Solubility Soluble in methanol.
Vapor Presure 1.84E-05mmHg at 25°C
Appearance Crystalline powder
Color Light Brown
pKa 2.95±0.25(Predicted)
Storage Condition 2-8°C
Refractive Index 1.618
MDL MFCD06208351

Product Detail

Product Tags

Hazard Symbols Xn - Harmful
Risk Codes R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code 29224999

 

Uses: As an intermediate in organic synthesis, it can be used to synthesize a variety of drugs, dyes and other organic compounds. In drug synthesis, it is an important raw material for the preparation of some drugs with specific biological activities; In dye synthesis, it can be used to construct dye molecules with specific structures and colors.
Safety Information
Hazard Statement: Harmful to swallow, can cause skin irritation, severe eye irritation, and may cause respiratory irritation.
Precautionary measures: Avoid inhaling dust, smoke, etc., and wear protective gloves, protective clothing, goggles, etc. In case of accidental contact, rinse immediately with plenty of water and seek medical attention promptly.

Application
5-Amino-2-methylbenzoic acid (5-Amino-o-toluic acid, CAS 2840-04-2) is a high-purity, functionalized benzoic acid derivative utilized as a key pharmaceutical intermediate in targeted drug discovery. This versatile heterocyclic building block is a critical precursor for synthesizing dihydroxylphenyl amides as potent Hsp90 inhibitors and 2,5-diaminopyrimidine derivatives as selective Bruton’s tyrosine kinase (BTK) inhibitors for oncology research. It also serves as Nilotinib Impurity 46, an essential reference standard for analytical method development, quality control, and ANDA filings. In pharmaceutical R&D, this scaffold enables rapid construction of anti-inflammatory, antimicrobial, and antiviral drug candidates. Its amino and carboxylic acid groups allow amide coupling and further functionalization for structure-activity relationship studies. Additionally, it is used in dye synthesis, agrochemical development, and as a monomer for high-performance polymers and coordination polymers. High purity ensures reproducible results in high-throughput screening and scalable GMP manufacturing. Xinchem offers reliable custom synthesis and contract manufacturing of 5-amino-2-methylbenzoic acid with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote.


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