6-Benzothiazolol(7CI,8CI,9CI)(CAS#13599-84-3)

Introduction

6-Hydroxybenzothiazole (-) is an organic compound with a chemical formula of C7H5NOS and a molecular weight of 159.18g/mol. The following is a description of some properties, uses, preparation methods and safety information of 6-hydroxybenzothiazole:

Nature:

-Appearance: 6-Hydroxybenzothiazole is a colorless or pale yellow solid.

-Solubility: It is insoluble in water, but can be dissolved in some organic solvents, such as ethanol, dichloromethane and ether.

-Melting point: The melting point of 6-hydroxybenzothiazole is about 275-280°C.

Use:

-Mordant: 6-hydroxybenzothiazole can be used as a raw material for dyes and mordants.

-Preservative: It can also be used as a preservative for certain products (such as coatings and adhesives), with anti-mold and antibacterial properties.

Preparation Method:

-6-hydroxybenzothiazole can be obtained by the reaction of the nitro derivative of benzothiazole and ethanol.

-The chemical method can also be obtained by the reaction of thiol derivatives of benzothiazole and hydrogen peroxide.

Safety Information:

-6-Hydroxybenzothiazole is a relatively safe compound under normal use conditions. However, any new chemicals should be used properly and safe handling precautions should be followed.

-Avoid inhalation, contact with skin and eyes when using 6-hydroxybenzothiazole. In case of accidental contact, rinse immediately with clean water and seek medical advice.

-When handling and storing 6-hydroxybenzothiazole, pay attention to fire and explosion prevention measures, and store it in a closed container, away from fire sources and oxidants.

Application
6-Hydroxybenzothiazole (6-Benzothiazolol, CAS 13599-84-3) is a versatile heterocyclic building block widely used across pharmaceutical, material science, and analytical research. As a multifunctional platform, this benzothiazole derivative exhibits a broad spectrum of biological activities, including antibacterial, antifungal, anticancer, anti-inflammatory, and antitubercular properties, making it a valuable scaffold for developing new drug candidates. It serves as a key precursor in the synthesis of aryl trifluoromethyl ethers and as a critical intermediate in the chemiluminescent synthesis of firefly luciferin. In material science, it functions as an effective corrosion inhibitor, forming protective layers on metal surfaces for automotive and industrial applications, and enhances thermal stability and UV resistance as a polymer additive. Its application extends to analytical chemistry as a selective fluorescent probe for detecting heavy metal ions. Additionally, due to its strong anti-mold and antibacterial properties, 6-hydroxybenzothiazole is also used as an industrial preservative in coatings, adhesives, and other products. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 6-hydroxybenzothiazole with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.