7-isoquinolinecarboxylic acid(CAS#221050-96-0)

Application
7-Isoquinolinecarboxylic acid (isoquinoline-7-carboxylic acid, CAS 221050-96-0) is a heterocyclic building block featuring a carboxylic acid group at the 7-position of the isoquinoline core. It is widely used in medicinal chemistry and pharmaceutical research for the synthesis of bioactive molecules, including kinase inhibitors, PARP inhibitors, and G-protein coupled receptor (GPCR) modulators. The carboxylic acid enables amide bond formation with amines, allowing rapid construction of diverse drug-like libraries for structure-activity relationship (SAR) studies. This scaffold is also utilized in the synthesis of potential anticancer, anti-inflammatory, antimicrobial, and neurological disorder therapeutics. In organic synthesis, it serves as a versatile intermediate for C–H functionalization and cross-coupling reactions. Additionally, it is employed in the development of fluorescent probes, coordination polymers, metal-organic frameworks (MOFs), and agrochemicals. High purity ensures reproducible results in high-throughput screening and scalable GMP synthesis. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 7-isoquinolinecarboxylic acid with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.