Methyl 3-hydrazinopyridaz(CAS#1234616-16-0)
Introduction
The following is an introduction to its properties, uses, manufacturing methods and safety information:Quality:- Appearance: Methyl 3-hydrazinopyridaz is a white solid powder.- Solubility: Can be dissolved in some polar organic solvents such as ethanol, acetone and dimethyl sulfoxide.- Stability: It is relatively stable, but should avoid prolonged exposure to sunlight or contact with strong oxidants.Use:Methyl 3-hydrazinopyridaz is often used as an important intermediate in organic synthesis chemical reactions.Method:The preparation method of Methyl 3-hydrazinopyridaz is more complex, and only a brief overview is provided here. A common preparation method is to start with the corresponding compound and go through a series of reaction steps to synthesize. The specific synthetic route involves reactions such as hydrogenation, substitution, and coupling.Safety Information:- Methyl 3-hydrazinopyridaz is an organic compound that may cause harm to humans. Appropriate safety measures should be taken during handling, including the wearing of protective eyewear, gloves and appropriate protective clothing.- Care should be taken to prevent the risk of fire and explosion during the storage and handling of Methyl 3-hydrazinopyridaz.
Application
Methyl 3-hydrazinopyridazine-6-carboxylate (CAS 1234616-16-0) is a high-purity hydrazine-functionalized pyridazine building block widely used in drug discovery and medicinal chemistry. As a key pharmaceutical intermediate, its hydrazino group enables the synthesis of pyridazinone, triazole, and other heterocyclic scaffolds with diverse bioactivity. Derivatives of 3-hydrazinopyridazine are reported to possess promising pharmacological properties as antihypertensive agents, anti-inflammatory compounds, chemotherapeutics, and CNS modulators. The hydrazinyl moiety readily forms hydrazones with carbonyl compounds, facilitating rapid library construction for SAR studies, while the methyl ester allows further derivatization via hydrolysis or amidation. This scaffold serves as a versatile precursor for developing targeted covalent inhibitors, enzyme modulators (such as inhibitors of pyridoxal-phosphate dependent enzymes), and novel therapeutic candidates with potential applications in oncology, cardiovascular diseases, and neurological disorders. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this key pyridazine building block. Contact us today for a competitive quote and reliable global supply.
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