Pyrrolo[2,3-c]pyridine-3-ylamine dihydrochloride(CAS#1257535-55-9)

Chemical Property:

Molecular Formula	C7H9Cl2N3
Molar Mass	206.07246
Storage Condition	2-8℃

Send email to us

Product Detail

Product Tags

Introduction

3-Amino-6-azaindole dihydrochloride is an organic compound. The following is an introduction to some properties, uses, preparation methods and safety information about 3-amino-6-azaindole dihydrochloride:Quality:- 3-Amino-6-azaindole dihydrochloride is a white to pale yellow solid powder.- It has a high solubility in water and is soluble in many organic solvents.- It is relatively stable in air, but photosensitivity reactions may occur when exposed to bright light.Use:- 3-Amino-6-azaindole dihydrochloride has a wide range of applications in the field of organic synthesis.Method:- The preparation of 3-amino-6-azaindole dihydrochloride can be accomplished by the synthetic route.- One synthesis method is to first react indole-3-carboxaldehyde with ethyl thionoxyacetate to form indole-3-carboxaldehyde sulfite, and then react this sulfite with hydrochloric acid and ammonia to obtain 3-amino-6-azaindole dihydrochloride.Safety Information:- 3-Amino-6-azaindole dihydrochloride does not cause significant harm to humans under normal conditions.- Close contact or inhalation of dust may cause irritation and allergic reactions.

Application
Pyrrolo[2,3-c]pyridine-3-ylamine dihydrochloride (CAS 1257535-55-9) is a nitrogen-rich heterocyclic building block featuring a fused pyrrole-pyridine core with an amine at position 3. As a purine bioisostere and azaindole analog, it is widely employed in medicinal chemistry for the development of selective kinase inhibitors targeting cancer, inflammatory diseases, and neurological disorders. The amine group enables amide, urea, or sulfonamide formation, while the dihydrochloride salt form improves water solubility and handling stability. This scaffold facilitates rapid structure-activity relationship (SAR) studies and serves as a versatile intermediate for synthesizing drug candidates such as JAK, BTK, and CDK inhibitors. It also finds applications in agrochemical research and fragment-based drug discovery. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this high-purity compound with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.