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4-(4,6-Dichloropyrimidin-2-yl)morpholine(CAS#10397-13-4)

Chemical Property:

Molecular Formula C8H9Cl2N3O
Molar Mass 234.08
Density 1.435±0.06 g/cm3(Predicted)
Melting Point 139.0 to 143.0 °C
Boling Point 392.9±52.0 °C(Predicted)
Flash Point 191.425°C
Vapor Presure 0mmHg at 25°C
Appearance White to white-like solid
pKa -1.07±0.50(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index 1.577
MDL MFCD05022359

Product Detail

Product Tags

HS Code 29349990

 

Introduction

2-Morpholino-4, 6-dichloropyrimidine, also commonly known as 2-MDP, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:

 

Nature:

2-morpholino-4, 6-dichloropyrimidine is a solid compound with a chemical formula of C7H6Cl2N2 and a relative molecular mass of 177.04g/mol. It has the appearance of white to yellow crystals and its melting point is between 120-125°C. It has low solubility in water, but has good solubility in organic solvents such as alcohols and ketones.

 

Use:

2-morpholino-4, 6-dichloropyrimidine has a wide range of applications in the field of medicine. It is often used as a pharmaceutical intermediate for the preparation of various drugs. It is widely used in the synthesis of anti-cancer drugs and anti-metabolic disease drugs. It can also be used in cosmetics and personal care products.

 

Preparation Method:

The preparation of 2-morpholinyl-4, 6-dichloropyrimidine can be obtained by the reaction of 2-morpholinecarboxaldehyde and 2-chloro-4, 6-dinitropyrimidine. Specific synthetic methods can be further referred to the organic chemical synthesis manual.

 

Safety Information:

2-Morpholino-4, 6-dichloropyrimidine is generally relatively safe under normal conditions of use. However, as an organic compound, exposure to it may cause irritation. Appropriate protective measures such as gloves and goggles should be worn during handling. When stored, it should be kept in a closed container and away from fire and oxidizing agents. If taken by mistake or inhaled by mistake, seek medical attention immediately.

Application
4-(4,6-Dichloropyrimidin-2-yl)morpholine is a versatile heterocyclic building block used in agrochemical and pharmaceutical R&D. In crop protection, it is a key intermediate for developing herbicides with targeted action against weeds, improving crop yields. In pharmaceutical research, it is utilized in the synthesis of antiviral drug candidates and as a scaffold for kinase inhibitors in cancer research. The compound supports material science applications, providing stability in polymers and coatings. It is also employed in biochemical assays to study enzyme activity and disease mechanisms. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 4-(4,6-Dichloropyrimidin-2-yl)morpholine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.


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