4-Amino-2-(methylthio)-6-pyrimidinol(CAS#1074-41-5)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29335990 |
Application
4-Amino-2-(methylthio)-6-pyrimidinol (CAS 1074-41-5) is a multifunctional pyrimidine derivative used as a key intermediate in medicinal chemistry and organic synthesis. Its unique substitution pattern (amino, methylthio, and hydroxyl groups) enables diverse derivatization for drug discovery. This compound is reported to induce phase II antioxidant enzymes, showing potential for chemoprevention and treatment of oxidative stress-related diseases. It also serves as a building block for synthesizing kinase inhibitors, antiviral agents, and antibacterial compounds. The pyrimidine core is a privileged scaffold in pharmaceuticals, and the methylthio group can be oxidized or displaced, while the amino and hydroxyl groups allow amide/ester formation. This intermediate is also valuable in agrochemical research and as a reference standard. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 4-amino-2-(methylthio)-6-pyrimidinol with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.







