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4-Aminomethylpyridazine hydrochloride(CAS#1351479-13-4)

Chemical Property:

Molecular Formula C5H8ClN3
Molar Mass 145.59012
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Sensitive Irritant
MDL MFCD16988465

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Introduction

4-Aminomethylpyridazine hydrochloride is an organic compound.Quality:4-Aminmethylpyrazine hydrochloride is a colorless crystalline solid, soluble in water and alcohol solvents, insoluble in non-polar solvents. It is weakly acidic.Use:Method:The preparation method of 4-aminomethylpyrazine hydrochloride can be obtained by reacting pyrazine with methylamine in an alcohol solvent. The resulting 4-aminomethylpyrazine is then reacted with hydrochloric acid to obtain 4-aminomethylpyrazine hydrochloride.Safety Information:The safety of 4-aminomethylpyrazine hydrochloride needs to be evaluated and treated according to the specific use and operation. As a chemical, it can be irritating and dangerous to the human body. Appropriate precautions should be taken during use, including wearing protective gloves, goggles, and protective clothing. During storage and handling, contact with oxidants and strong acids should be avoided, and ignition sources and high temperatures should be avoided. Storage, transportation and handling should be carried out in accordance with relevant regulations and regulations. Take care to follow proper laboratory practices.

Application

4-Aminomethylpyridazine hydrochloride (CAS 1351479-13-4) is a premium heterocyclic building block specifically designed for advanced pharmaceutical R&D and custom synthesis projects. As a highly functionalized pyridazine derivative, it features a reactive aminomethyl group that enables efficient amide coupling, reductive amination, and nucleophilic substitution reactions. This scaffold is extensively utilized as a pharmaceutical intermediate in medicinal chemistry for the synthesis of targeted covalent inhibitors, kinase modulators, and CNS-penetrant therapeutics. The pyridazine core has gained significant traction in drug development for oncological indications, with additional applications in inflammation, hypertension, and cardiovascular disease research. Its versatility allows seamless integration into diverse discovery workflows, from hit-to-lead optimization to preclinical candidate synthesis. Xinchem supports all stages of pharmaceutical development with flexible custom synthesis and contract manufacturing solutions. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this high-purity compound with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.


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