4-Chloro-3-ethylphenol(CAS#14143-32-9)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29071990 |
Introduction
4-Chloro-3-ethylphenol, also known as p-chloro-p-ethylphenol, is an organic compound. The following describes its nature, use, preparation and safety information:
Nature:
-Appearance: 4-Chloro-3-ethylphenol is a colorless or white crystalline solid.
-Solubility: It is soluble in alcohol and ether solvents, slightly soluble in water.
Use:
-Fungicide: It has bactericidal, antibacterial and antifungal properties, and is commonly used as a topical fungicide, such as in soap, hand sanitizer, detergent and other products.
-Medical use: 4-Chloro-3-ethylphenol is also used as a pharmaceutical intermediate for the synthesis of some drugs.
Preparation Method:
-4-Chloro-3-ethylphenol can be prepared by reacting p-ethylphenol with phosphorus pentachloride. The specific synthesis steps need to be carried out in the chemical laboratory, which requires certain chemical knowledge and experimental operation skills.
Safety Information:
-For any chemical substance, carefully read and follow the operating instructions in the safety data sheet (SDS) before use. 4-Chloro-3-ethylphenol should be handled under suitable laboratory conditions.
-It is a toxic substance, contact or inhalation of 4-chloro-3-ethylphenol may cause health hazards. Care should be taken to avoid direct contact with skin and eyes and to ensure adequate ventilation.
-During handling and storage, the relevant safety procedures should be strictly observed and properly stored to prevent contact with ignition or oxidizing agents.
-In case of inhalation, ingestion or skin contact, rinse immediately with plenty of water and seek medical attention.
Please note that in the process of using 4-chloro-3-ethylphenol or any other chemical substances, relevant regulations should be followed and appropriate safety measures should be taken.
Application
4-Chloro-3-ethylphenol (CAS 14143-32-9) is a high-purity chlorinated phenol serving as a versatile pharmaceutical intermediate and research biochemical. Functioning as a potent ryanodine receptor antagonist, it is extensively utilized as a research tool and diagnostic reagent for malignant hyperthermia studies and calcium signaling research. It also exhibits significant antibacterial, bactericidal, and antifungal properties, making it a common topical fungicide in soaps, hand sanitizers, and detergents. As a key building block for organic synthesis, it participates in cross-coupling reactions and pharmaceutical synthesis. In environmental applications, it is used in wastewater treatment and can be detected via fluorescence probes. Additionally, it serves as a valuable HPLC reference standard for analytical method development. Xinchem offers custom synthesis and contract manufacturing of high-purity 4-Chloro-3-ethylphenol with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.







