Methylcyclohexanone(CAS#1331-22-2)
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R10 - Flammable R22 - Harmful if swallowed |
| Safety Description | 16 - Keep away from sources of ignition. |
| UN IDs | UN 2297 3/PG 3 |
| WGK Germany | 1 |
| RTECS | GW1575000 |
Introduction
Methylcyclohexanone. The following is a brief introduction to the properties, uses, preparation methods and safety information of methylcyclohexanone: Properties: Appearance: colorless liquid, with a special aroma. Density: 0.948 g/cm³ Solubility: soluble in alcohol and ether solvents, insoluble in water. Stability: Stable, but can be dangerous when exposed to high temperatures, open flames and oxidizing agents. Toxicity: Methylcyclohexanone has certain toxicity, and safe operating procedures should be observed during use and storage. Uses: Preparation method: Methylcyclohexanone can be obtained by the reaction of cyclohexanone and methanol in the presence of acid catalyst. The specific preparation method is as follows: Preparation requirements: cyclohexanone, methanol and acid catalyst (such as sulfuric acid, etc.). Experimental procedure: Cyclohexanone and methanol are mixed in a certain molar ratio, heated and stirred at an appropriate temperature in the presence of acid catalyst, and after a period of reaction, methylcyclohexanone can be obtained by distillation and condensation under reduced pressure. Safety information: Methylcyclohexanone is irritating and toxic, so care should be taken to avoid skin, eye and respiratory exposure, and appropriate personal protective equipment should be worn when using it. Avoid contact with strong oxidizing agents and flammable substances to prevent the risk of fire and explosion. When storing, it should be kept away from fire and high temperatures, and keep the container tightly closed.
Application
Methylcyclohexanone (CAS 1331-22-2) is a high-purity isomer mixture (2-, 3-, and 4-methylcyclohexanone) valued as a medium-boiling, slow-evaporating ketone solvent and a versatile industrial intermediate. It exhibits excellent solvency for nitrocellulose, acrylics, alkyds, polyurethanes, and epoxy resins, making it a key component in high-performance lacquers, varnishes, automotive coatings, industrial paints, printing inks, and wood finishes. In the adhesives and sealants industry, it improves wetting, reduces viscosity, and acts as a crosslinking agent, enhancing bond strength, plasticizer compatibility, and flexibility for structural adhesives and polyurethane sealants. As an organic solvent, methylcyclohexanone effectively removes grease, oil, rust, and machining residues from metal surfaces and is utilized in cleaning formulations for metalworking, electronics, and precision parts. The compound is a critical chemical intermediate and pharmaceutical building block in the synthesis of APIs, anti-inflammatory agents, anticancer drugs, antifungals, and active pharmaceutical intermediates. In agricultural chemistry, it serves as a pesticide intermediate for manufacturing herbicides, insecticides, and fungicides. Additionally, methylcyclohexanone is used as a reactant in polymerization processes to engineer specialty polymers, resin modifiers, and polymer additives, and as an extraction solvent, a diluent for textile dyeing auxiliaries, and a leather degreasing agent. With its strong solvency, balanced evaporation rate, good diluent tolerance, and low water miscibility, methylcyclohexanone is an essential solvent and intermediate for industrial coatings, chemical synthesis, and high-purity manufacturing. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of methylcyclohexanone with flexible scaling from R&D to commercial tons. Contact us for a competitive quote and reliable global supply.







